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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7870 | TCN 201 | TCN-201 | NMDAR , iGluR |
TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit. | |||
T8450 | TCN 213 | TCN213 | NMDAR |
TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B | |||
T7494 | TCN238 | TCN 238 | GluR |
TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM). | |||
T6065 | Triciribine | VD-0002,Tricyclic nucleoside,NSC 154020,API-2,TCN | Akt , HIV Protease , DNA/RNA Synthesis |
Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2. | |||
T19699 | Triciribine phosphate | TCN-P,VD 002,VQD-002 | Apoptosis , Akt |
Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia. | |||
T23440 | TC-N 22A | GluR | |
TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier. EC50 expression of TC-N 22A in BHK cells expressing human mGlu4 was 9 nM. TC-N 22A showed very... | |||
T23439 | TC-N 1752 | Sodium Channel | |
TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities. |