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Search Results for " st2 "

Targets

7

Compounds

26

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9988 Wnt/β-catenin agonist 3 Wnt/beta-catenin
Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.
T20920 PST2286 PST 2286,17Hydroxydigitoxigenin,17-Hydroxydigitoxigenin,17 Hydroxydigitoxigenin,PST-2286 Others
PST2286 (17-Hydroxydigitoxigenin) is a rostafuroxin metabolite.
T4511 ST271 ST 271 Phospholipase , Tyrosine Kinases
ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
T72015 IST2-1
iST2-1 is a first-in-class ST2 inhibitor active in vivo.
T62321 ST247
ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/...
T77083 Melrilimab
Melrilimab (GSK 3772847), an IgG2-kappa monoclonal antibody targeting IL1RL1/ST2/IL33R/DER4/FIT-1, is utilized in asthma research [1].
T80759 XY-52
XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasm...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04096 ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) Mouse HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-03493 ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-02147 ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPJ-00849 ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-05452 ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-01587 SULT2A1 Protein, Human, Recombinant (His) Human E. coli
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotra...
TMPY-03235 BST2 Protein, Human, Recombinant (His) Human HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-03193 BST2 Protein, Human, Recombinant (hFc) Human HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-02674 BST2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-02510 HIST2H2BE Protein, Human, Recombinant Human E. coli
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. Histone proteins exhibit two levels of diversity: 1. evolutionary diversity between species and...
TMPY-04742 BST2 Protein, Mouse, Recombinant (His) Mouse HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPK-01298 BST2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res...
TMPY-00846 IL-18BP Protein, Human, Recombinant (His) Human HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPY-05492 IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) Human HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPY-01111 IL-18BP Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ...
TMPK-00163 IL-33 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are exp...
TMPK-00332 IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) Human HEK293
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R...
TMPK-00638 IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R...
TMPJ-00617 IL-33 Protein, Rhesus macaque, Recombinant (His) Rhesus macaque E. coli
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the pr...
TMPK-00333 IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R...
TMPY-01001 SDF-2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 a...
TMPY-02274 SDF-2 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 a...
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)
TMPY-04096
Species: Mouse
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant
TMPY-00850
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
TMPY-00849
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
TMPY-01359
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
TMPJ-00850
Species: Mouse
Expression System: Human Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc)
TMPY-03493
Species: Mouse
Expression System: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)
TMPY-02147
Species: Human
Expression System: HEK293
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)
TMPJ-00849
Species: Mouse
Expression System: Human Cells
ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His)
TMPY-05452
Species: Cynomolgus
Expression System: HEK293
SULT2A1 Protein, Human, Recombinant (His)
TMPY-01587
Species: Human
Expression System: E. coli
BST2 Protein, Human, Recombinant (His)
TMPY-03235
Species: Human
Expression System: HEK293
BST2 Protein, Human, Recombinant (hFc)
TMPY-03193
Species: Human
Expression System: HEK293
BST2 Protein, Mouse, Recombinant (hFc)
TMPY-02674
Species: Mouse
Expression System: HEK293
HIST2H2BE Protein, Human, Recombinant
TMPY-02510
Species: Human
Expression System: E. coli
BST2 Protein, Mouse, Recombinant (His)
TMPY-04742
Species: Mouse
Expression System: HEK293
BST2 Protein, Cynomolgus, Recombinant (His)
TMPK-01298
Species: Cynomolgus
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (His)
TMPY-00846
Species: Human
Expression System: HEK293
IL-18BP Protein, Human, Recombinant (aa 1-192, hFc)
TMPY-05492
Species: Human
Expression System: HEK293
IL-18BP Protein, Mouse, Recombinant (His)
TMPY-01111
Species: Mouse
Expression System: HEK293
IL-33 Protein, Cynomolgus, Recombinant (His)
TMPK-00163
Species: Cynomolgus
Expression System: HEK293
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi)
TMPK-00332
Species: Human
Expression System: HEK293
IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His)
TMPK-00638
Species: Cynomolgus
Expression System: HEK293
IL-33 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00617
Species: Rhesus macaque
Expression System: E. coli
IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00333
Species: Human
Expression System: HEK293
SDF-2 Protein, Human, Recombinant (His)
TMPY-01001
Species: Human
Expression System: Baculovirus-Insect Cells
SDF-2 Protein, Mouse, Recombinant (His)
TMPY-02274
Species: Mouse
Expression System: Baculovirus-Insect Cells
TargetMol