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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11035 | DiABZI STING agonist-1 (Tautomerism) | diABZI STING agonist (Compound 3) | STING |
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | |||
T13015 | STING agonist-4 | STING | |
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM). | |||
T8328 | STING agonist-1 | G10 | Virus Protease , STING |
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses. | |||
T9853 | STING activator Compound 53 | STING | |
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons... | |||
T9028 | STING-IN-2 | C-170 | STING |
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research. | |||
T9029 | STING-IN-3 | C-171 | STING |
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. | |||
T5516 | DiABZI STING agonist-1 trihydrochloride | STING | |
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist. | |||
T60000 | STING (WT/R232) activity regulator 126 | STING | |
STING (WT/R232) activity regulator 126 is a STING modulator with antibacterial and antiviral effects. | |||
T38161 | STING Agonist C11 | STING Agonist C11 | |
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory... | |||
T74809 | STING agonist-30 | STING , Antifection | |
STING agonist-30 is a potent STING agonist that triggers STING-dependent immune activation.STING agonist-30 shows broad-spectrum inhibitory effects against a variety of viruses including HSV (Herpes Simplex Virus), rotav... | |||
T5154 | C-176 | C176,STING inhibitor 1 | STING |
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor | |||
T13014L | STING agonist-3 trihydrochloride | STING agonist-3 trihydrochloride (2138299-29-1 free base) | Others |
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatme... | |||
T38159 | STING Agonist 12b | ||
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 ... | |||
T38160 | STING Agonist 1a | ||
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expres... | |||
T13906 | STING ligand-1 | Others | |
STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING). | |||
T13014 | STING agonist-3 | Others | |
STING agonist-3 is a selective and non-nucleotide small-molecule STING agonist(pEC50 and pIC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer. | |||
T75161 | STING agonist-31 | ||
STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively, demonstrating significant antitumor efficacy [1]. | |||
T74621 | STING agonist-9 | ||
STING Agonist-9 (Compound 45) is a powerful stimulator of the STING pathway, demonstrating potent activity with an EC50 of 1.2 nM against human STING (h-STING) and 32.82 μM against mouse STING (m-STING). It exhibits anti... | |||
T63458 | STING agonist-11 | ||
STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy. | |||
T72688 | STING agonist-20 | ||
STING agonist-20, a potent agonist utilized in the synthesis of XMT-2056, serves as a vaccine adjuvant for cancer and various inflammatory immune diseases research. |