Powder: -20°C for 3 years
In solvent: -80°C for 2 years
C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.
Description | C-170 is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research. |
In vitro | In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels |
Synonyms | C-170 |
Molecular Weight | 288.3 |
Formula | C15H16N2O4 |
CAS No. | 346691-38-1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 22.5 mg/mL (78.04 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
STING-IN-2 346691-38-1 Immunology/Inflammation STING Inhibitor autoinflammatory ERIS MPYS cGAMP MITA IFNB1 STING IN 2 Stimulator of Interferon Genes TMEM173 inhibit palmitoylation STINGIN2 C-170 p-TBK1 TNF inhibitor