Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STING agonist-3 is a selective and non-nucleotide small-molecule STING agonist(pEC50 and pIC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 155.00 | |
1 mg | 35 days | $ 288.00 | |
5 mg | 35 days | $ 1,190.00 | |
10 mg | 35 days | $ 1,980.00 |
Description | STING agonist-3 is a selective and non-nucleotide small-molecule STING agonist(pEC50 and pIC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer. |
In vitro | STING agonist-3 exhibits activation of STING in cells(pEC50 of 7.5), this assay is determined using a luciferase reporter assay in human embryonic kidney cells (HEK293T) co-transfected with plasmids expressing STING and the enzyme firefly luciferase driven by the interferon stimulated response element promoter.In FRET assay, STING agonist-3 exhibits a pIC50 value of 9.5 . This is a competition binding assay which aims to determine the binding potency of molecules to the C-terminal Domain (CTD) of human STING. |
Molecular Weight | 750.81 |
Formula | C37H42N12O6 |
CAS No. | 2138299-29-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (166.49 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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STING agonist-3 2138299-29-1 Others STING agonist 3 STING agonist3 inhibitor inhibit