Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 45.00 | |
25 mg | In stock | $ 85.00 | |
50 mg | In stock | $ 134.00 | |
100 mg | In stock | $ 207.00 | |
200 mg | In stock | $ 310.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 51.00 |
Description | STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. |
In vitro | C-171 binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM[1]. |
Synonyms | C-171 |
Molecular Weight | 316.35 |
Formula | C17H20N2O4 |
CAS No. | 2244881-69-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.16 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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STING-IN-3 2244881-69-2 Immunology/Inflammation STING genes inhibit ERIS TMEM173 mmSTING C171 Inhibitor Stimulator of Interferon Genes MPYS MITA C 171 stimulator C-171 hsSTING STINGIN3 interferon STING IN 3 inhibitor