Powder: -20°C for 3 years
In solvent: -80°C for 2 years
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Description | C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. |
In vitro | C-171 binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM[1]. |
Synonyms | C-171 |
Molecular Weight | 316.36 |
Formula | C17H20N2O4 |
CAS No. | 2244881-69-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 3.16 mg/mL (10 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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STING-IN-3 2244881-69-2 Immunology/Inflammation STING genes inhibit ERIS TMEM173 mmSTING Inhibitor Stimulator of Interferon Genes MPYS MITA C-171 stimulator hsSTING STINGIN3 interferon STING IN 3 inhibitor