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STING-IN-3
🥰Excellent
Catalog No. T9029Cas No. 2244881-69-2
Alias C-171
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
STING-IN-3
🥰Excellent
Purity: 99.08%
Catalog No. T9029Alias C-171Cas No. 2244881-69-2
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $45 | In Stock | |
| 25 mg | $85 | In Stock | |
| 50 mg | $134 | In Stock | |
| 100 mg | $207 | In Stock | |
| 200 mg | $310 | In Stock |
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CitedSelect Batch
Purity:99.08%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. |
| In vitro | C-171 binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM[1]. |
| Alias | C-171 |
| Molecular Weight | 316.35 |
| Formula | C17H20N2O4 |
| Cas No. | 2244881-69-2 |
| Smiles | CCCCCCc1ccc(NC(=O)c2ccc(o2)[N+]([O-])=O)cc1 |
| Relative Density. | 1.208 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 3.16 mg/mL (9.99 mM), Sonication is recommended.  | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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