Powder: -20°C for 3 years
In solvent: -80°C for 2 years
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Description | STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation. |
Targets&IC50 | STING:185 nM (EC50) |
Molecular Weight | 490.88 |
Formula | C25H19ClF4N2O2 |
CAS No. | 2259624-71-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 50 mg/mL (101.86 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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STING activator Compound 53 2259624-71-8 Immunology/Inflammation STING Inhibitor HEK293T STING agonist-12 MPYS STING agonist12 STING agonist 12 TMEM173 inhibit ERIS Stimulator of Interferon Genes MITA inhibitor