Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 422.00 | |
100 mg | In stock | $ 628.00 | |
500 mg | In stock | $ 1,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation. |
Targets&IC50 | STING:185 nM (EC50) |
Molecular Weight | 490.88 |
Formula | C25H19ClF4N2O2 |
CAS No. | 2259624-71-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (101.86 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
STING activator Compound 53 2259624-71-8 Immunology/Inflammation STING Inhibitor HEK293T STING agonist-12 MPYS STING agonist12 STING agonist 12 TMEM173 inhibit ERIS Stimulator of Interferon Genes MITA inhibitor