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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9988 | Wnt/β-catenin agonist 3 | Wnt/beta-catenin | |
Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist. | |||
T20920 | PST2286 | PST 2286,17Hydroxydigitoxigenin,17-Hydroxydigitoxigenin,17 Hydroxydigitoxigenin,PST-2286 | Others |
PST2286 (17-Hydroxydigitoxigenin) is a rostafuroxin metabolite. | |||
T4511 | ST271 | ST 271 | Phospholipase , Tyrosine Kinases |
ST271 is an effective protein tyrosine kinase (PTK) inhibitor. | |||
T72015 | IST2-1 | ||
iST2-1 is a first-in-class ST2 inhibitor active in vivo. | |||
T62321 | ST247 | ||
ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/... | |||
T77083 | Melrilimab | ||
Melrilimab (GSK 3772847), an IgG2-kappa monoclonal antibody targeting IL1RL1/ST2/IL33R/DER4/FIT-1, is utilized in asthma research [1]. | |||
T80759 | XY-52 | ||
XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasm... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04096 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-00850 | ST2/IL-1 RL1 Protein, Human, Recombinant | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-00849 | ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-01359 | ST2/IL-1 RL1 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | Human Cells |
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes.... | |||
TMPY-03493 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-02147 | ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPJ-00849 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) | Mouse | Human Cells |
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes.... | |||
TMPY-05452 | ST2/IL-1 RL1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-01587 | SULT2A1 Protein, Human, Recombinant (His) | Human | E. coli |
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotra... | |||
TMPY-03235 | BST2 Protein, Human, Recombinant (His) | Human | HEK293 |
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons... | |||
TMPY-03193 | BST2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons... | |||
TMPY-02674 | BST2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons... | |||
TMPY-02510 | HIST2H2BE Protein, Human, Recombinant | Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. Histone proteins exhibit two levels of diversity: 1. evolutionary diversity between species and... | |||
TMPY-04742 | BST2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons... | |||
TMPK-01298 | BST2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune res... | |||
TMPY-00846 | IL-18BP Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-05492 | IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-01111 | IL-18BP Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPK-00163 | IL-33 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are exp... | |||
TMPK-00332 | IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R... | |||
TMPK-00638 | IL-1 Rrp2/IL-1 R6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R... | |||
TMPJ-00617 | IL-33 Protein, Rhesus macaque, Recombinant (His) | Rhesus macaque | E. coli |
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the pr... | |||
TMPK-00333 | IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R... | |||
TMPY-01001 | SDF-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 a... | |||
TMPY-02274 | SDF-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 a... |