scd — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38826	Vibozilimod	Vibozilimod,SCD-044	S1P Receptor
	Vibozilimod (SCD-044) is S1P receptor-1 (S1PR1) agonist .		S1P Receptor
T5427	GSK1940029	SCD inhibitor 1	Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T6412	CVT-12012		Stearoyl-CoA Desaturase (SCD)
	CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).		Stearoyl-CoA Desaturase (SCD)
T4515	A939572		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T2650	MK-8245		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T13356	XEN723		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T14878	CAY10566		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally ...		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T16068	MF-438		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T9722	YTX-465		Stearoyl-CoA Desaturase (SCD)
	YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM).		Stearoyl-CoA Desaturase (SCD)
T3341	Elemicin	Elemicine,3,4,5-trimethoxyallylbenzene	Influenza Virus , 5-HT Receptor , Stearoyl-CoA Desaturase (SCD)
	Elemicin (Elemicine) is a constituent of several plant species' essential oils with anticholinergic effects in human.
T7581	Voxelotor	GBT 440	Others
	Voxelotor (GBT 440) is an inhibitor of sickle hemoglobin (HbS).		Others
T38683	SCD1 inhibitor-3	SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a	Dehydrogenase
	SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesit...		Dehydrogenase
T12863	SCD1 inhibitor-1		Others
	SCD1 inhibitor-1 is a potent and liver-selective inhibitor of stearoyl-CoA desaturase-1 (SCD1).		Others
T1869	PluriSIn 1	NSC 14613,PluriSIn #1,PluriSln 1	Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.		Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T75396	Sphingolipid ceramide N-deacylase (SCDase)
	Sphingolipid ceramide N-deacylase (SCDase) is an enzyme that catalyzes the cleavage of the N-acyl linkage between fatty acids and sphingosine bases in various glycosphingolipids, converting them into lysoglycosphingolipi...
T71175	SCD1 Inhibitor
	SCD1 Inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.
T61841	SCD1-IN-1
	SCD1-IN-1, a potent inhibitor of SCD1 (IC50: 5.8 nM), is valuable in dermatologic research [1].
T39520	Vamifeport	VIT-2763	Ferroptosis
	Vamifeport (VIT-2763) is a novel orally active inhibitor that targets iron transport proteins and reduces markers of hemolysis in the SCD Townes model.VIT-2763 improves anemia and erythropoiesis, ameliorates vascular inf...		Ferroptosis