Powder: -20°C for 3 years
In solvent: -80°C for 2 years
XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
Description | XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively). |
Targets&IC50 | SCD1:45 nM(in Mouse), SCD1:524 nM( in HepG2 cell) |
In vitro | XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively). XEN723 demonstrates an improvement in SCD1 in vitro potency of more than 560-fold compare to the original high throughput screen (HTS) hit. |
Molecular Weight | 425.48 |
Formula | C21H20FN5O2S |
CAS No. | 1072803-08-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 100 mg/mL (235.03 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XEN723 1072803-08-7 代谢 Dehydrogenase Stearoyl-CoA Desaturase (SCD) XEN-723 Inhibitor XEN 723 inhibit inhibitor