ras-related — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3971	CASIN	Pirl1-related Compound 2	CDK , STAT , Ras
	CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).		CDK , STAT , Ras
T7558	CID-1067700		Ras
	CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).		Ras
T7764	CCG-222740		ROCK , Rho , Ras
	CCG-222740 is an inhibitor of Rho/MRTF pathway		ROCK , Rho , Ras
T22991	ML-099		Rho , Ras
	pan activator of Ras-related GTPases		Rho , Ras
T21970	ML-097		GTPase
	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases		GTPase
T2700	FTI-277 hydrochloride	FTI 277 HCl	Apoptosis , Transferase , Ras
	FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.		Apoptosis , Transferase , Ras
T74698	RMC-6236	RAS-IN-2
	RMC-6236（RAS-IN-2) is a potent inhibitor of RAS(ON) MULTI, utilized in cancer research [1].
T3314	Perillyl alcohol	Isocarveol,Perilla alcohol	Apoptosis , Endogenous Metabolite
	Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-...		Apoptosis , Endogenous Metabolite
T9533	BC-LI-0186	4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...		Others
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T69618	XR3054
	XR3054 is a novel inhibitor of farnesyl protein transferase (FPTase). XR3054 inhibited the proliferation of the prostatic cancer cell lines LnCAP and PC3 and the colon carcinoma SW480 and HT1080 (IC50 values of 12.4, 12....
T72340	KRAS G12C inhibitor 37
	KRAS G12C Inhibitor 37, a potent inhibitor of KRAS G12C, targets the Ras family of proteins, crucial for intracellular signaling related to growth and development. This compound holds potential for research into cancers ...
T72344	KRAS G12C inhibitor 41
	KRAS G12C Inhibitor 41 is a potent agent targeting the KRAS G12C mutation within the Ras family of proteins, which are crucial for intracellular signaling related to growth and development. This compound holds significan...
T37496	Alamandine
	Alamandine can be formed from angiotensin A by action of ACE-2 or directly from angiotensin-(1-7) by decarboxylation of its aspartate residue. The angiotensin A analog produces effects resembling those of Ang II (1-7). H...