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Search Results for " ras "

20

Compounds

Cat No. Product Name Synonyms Targets
T37422L Ras Inhibitory Peptide acetate Ras Inhibitory Peptide acetate(159088-48-9 Free base) Ras
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors.
T16432 Pan-RAS-IN-1 MAPK , Ras
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
T5469 K-Ras-IN-1 Raf , Ras
K-Ras-IN-1 is a K-Ras inhibitor.
T11738 K-Ras G12C-IN-4 Ras
K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C..
T6556 K-Ras(G12C) inhibitor 9 Raf
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T3725 K-Ras(G12C) Inhibitor 6 Raf
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
T6555 K-Ras(G12C) inhibitor 12 Apoptosis , Raf , Ras
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T8659 K-Ras-PDEδ-IN-1 PDE
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).
T12692 RAS GTPase inhibitor 1 Others
RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity.
T36642 RAS/RAS-RAF-IN-1
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for ...
T36641 RAS inhibitor Abd-7
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ...
T37422 Ras Inhibitory Peptide
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to t...
T74698 RMC-6236 RAS-IN-2
RMC-6236(RAS-IN-2) is a potent inhibitor of RAS(ON) MULTI, utilized in cancer research [1].
T77800 Ras inhibitor 134
T11735 K-Ras G12C-IN-1 Phosphatase
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
T11737 K-Ras G12C-IN-3 Others
Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.
T11736 K-Ras G12C-IN-2 Others
K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.
T13844 PROTAC K-Ras Degrader-1 Ras
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
T18059 K-Ras ligand-Linker Conjugate 6 Others
K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker...
T18058 K-Ras ligand-Linker Conjugate 5 Others
K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. T...
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