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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37422L | Ras Inhibitory Peptide acetate | Ras Inhibitory Peptide acetate(159088-48-9 Free base) | Ras |
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors. | |||
T16432 | Pan-RAS-IN-1 | MAPK , Ras | |
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors. | |||
T5469 | K-Ras-IN-1 | Raf , Ras | |
K-Ras-IN-1 is a K-Ras inhibitor. | |||
T11738 | K-Ras G12C-IN-4 | Ras | |
K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C.. | |||
T6556 | K-Ras(G12C) inhibitor 9 | Raf | |
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T3725 | K-Ras(G12C) Inhibitor 6 | Raf | |
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. | |||
T6555 | K-Ras(G12C) inhibitor 12 | Apoptosis , Raf , Ras | |
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T8659 | K-Ras-PDEδ-IN-1 | PDE | |
K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM). | |||
T12692 | RAS GTPase inhibitor 1 | Others | |
RAS GTPase inhibitor 1 is a inhibitor of RAS GTPase, with anti-tumor activity. | |||
T36642 | RAS/RAS-RAF-IN-1 | ||
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activity[1]. RAS/RAS-RAF-IN-1 (compound 89; for ... | |||
T36641 | RAS inhibitor Abd-7 | ||
RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders ... | |||
T37422 | Ras Inhibitory Peptide | ||
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to t... | |||
T74698 | RMC-6236 | RAS-IN-2 | |
RMC-6236(RAS-IN-2) is a potent inhibitor of RAS(ON) MULTI, utilized in cancer research [1]. | |||
T77800 | Ras inhibitor 134 | ||
T11735 | K-Ras G12C-IN-1 | Phosphatase | |
K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C. | |||
T11737 | K-Ras G12C-IN-3 | Others | |
Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. | |||
T11736 | K-Ras G12C-IN-2 | Others | |
K-Ras G12C-IN-2 is a covalent kras g12c inhibitor. | |||
T13844 | PROTAC K-Ras Degrader-1 | Ras | |
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC. | |||
T18059 | K-Ras ligand-Linker Conjugate 6 | Others | |
K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker... | |||
T18058 | K-Ras ligand-Linker Conjugate 5 | Others | |
K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. T... |