rac1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2131L	Rac1 Inhibitor W56 acetate(1095179-01-3 free base)		Rho
	Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 acetate(1095179-01-3 free ...		Rho
T61448	AZA1	Rac1/Cdc42-IN-1	Apoptosis , Rho , CDK
	AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induced apoptosis of prostate cancer cells and inhibited cell proliferation, migration and invasion.		Apoptosis , Rho , CDK
T6342	NSC 23766 trihydrochloride	Rac1 Inhibitor,NSC 23766	Apoptosis , Rho , Ras
	NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.		Apoptosis , Rho , Ras
TP2131	Rac1 Inhibitor W56
	Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1. Rac1 Inhibitor W56 selectively inhibits Rac1 interaction with Rac1-specific G...
TP2130L	Rac1 Inhibitor F56, control peptide acetate	Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)	Rho
	Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.		Rho
TP2130	Rac1 Inhibitor F56, control peptide
	Control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.
T79869	Rac1-IN-3		Ras
	Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 μM [1].		Ras
T8527	CPYPP		Others
	CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY...		Others
T75932	Rac1 Inhibitor W56 TFA
	Rac1 Inhibitor W56 TFA, a peptide comprised of residues 45-60 of Rac1, selectively obstructs Rac1's interaction with the guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam [1].
T22991	ML-099		Rho , Ras
	pan activator of Ras-related GTPases		Rho , Ras
T2427	EHop-016	EHop 016	Rho , Ras
	EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.		Rho , Ras
T21970	ML-097		GTPase
	ML-097 (CID-2160985) is a pan activator of Ras-related GTPases		GTPase
T6483	EHT 1864	EHT 1864 2HCl	Rho , Ras
	EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).		Rho , Ras
T24833	ZINC69391	ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base)	Apoptosis , Rho
	ZINC69391 (CysHHC10 acetate(1408311-03-4 free base)) is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, reduces Rac1-GTP le...		Apoptosis , Rho
T37113	Z62954982	ZINC08010136	Rho
	Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary ...		Rho
T25450	GGTI 2147	GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147	NF-κB , Rho
	GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.		NF-κB , Rho
T14004	1A-116		Rho
	1A-116 is a specific inhibitor of Rac1 .		Rho
T1237	Azathioprine	BW 57-322	Apoptosis , GPR , Rho
	Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.		Apoptosis , GPR , Rho
T12452	Digeranyl bisphosphonate	DGBP	Rho , Ras
	Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl bisphosphonate induces autophagy but not apoptosis.		Rho , Ras
T15602	ITX3		Others , Rho
	ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in P...		Others , Rho