Search Result

Search Results for " rage "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1935L1	RAGE antagonist peptide acetate		Beta Amyloid
	RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflammatory activities. RAGE antagonist peptide acetate prevents ...		Beta Amyloid
TP1935	RAGE antagonist peptide
	Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and ...
T61721	RAGE 229
	RAGE 229, N-(4-(7-cyano-4-(morpholin-4ylmethyl) quinolin-2-yl)phenyl)acetamide, is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the...
T72824	RAGE/SERT-IN-1
	RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and 31.09 nM, respectively. It demonstrates a significant neurop...
T125142	Oleragenoside
	Oleragenoside is a useful organic compound for research related to life sciences. The catalog number is T125142 and the CAS number is 274677-98-4.
T35327	Carrageenan	kappa-Carrageenan	Antiviral
	Carrageenan is a useful organic compound for research related to life sciences. The catalog number is T35327 and the CAS number is 9000-07-1.		Antiviral
T124466	(Z)-23-Coumaroylhederagenin
	(Z)-23-Coumaroylhederagenin is a useful organic compound for research related to life sciences and the catalog number is T124466.
T3259	FPS-ZM1		Beta Amyloid , advanced glycation end products
	FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.		Beta Amyloid , advanced glycation end products
T39115	ABR-238901		TLR
	ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products) and TLR4 (toll-like receptor 4). ABR-238901 has potential a...		TLR
T2507	Azeliragon	TTP488	Beta Amyloid , advanced glycation end products
	Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-moderate Alzheimer_acute_s disease (AD).		Beta Amyloid , advanced glycation end products
T14390	Azelaprag	AMG 986	Apelin receptor
	Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases.		Apelin receptor
T24598	BrBzGCp2	p BrBzGSH(Cp)2,BBGC,pBrBzGSH(Cp)2,p-BrBzGSH(Cp)2,BBGD
	p-BrBzGSH(Cp)2 is a glyoxylase 1 inhibitor. In orthotopic mouse models, it acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth.
T2507L2	Azeliragon HCl	TTP488 HCl,Azeliragon hydrochloride,TTP 488,Azeliragon dihydrochloride,TTP-488
	Azeliragon is a potent and orally active inhibitor of RAGE (receptor for advanced glycation endproducts), a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the...
T35890	Pentosidine
	Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditi...

Compounds

RAGE antagonist peptide acetate

TP1935L1

Synonym:

Target: Beta Amyloid

RAGE antagonist peptide

Synonym: kappa-Carrageenan

Target: Antiviral

(Z)-23-Coumaroylhederagenin

Target: Beta Amyloid, advanced glycation end products

Target: Beta Amyloid, advanced glycation end products

Azelaprag

T14390

Synonym: AMG 986

Target: Apelin receptor

BrBzGCp2

T24598

Synonym: p BrBzGSH(Cp)2,BBGC,pBrBzGSH(Cp)2,p-BrBzGSH(Cp)2,BBGD

Target:

Azeliragon HCl

T2507L2

Synonym: TTP488 HCl,Azeliragon hydrochloride,TTP 488,Azeliragon dihydrochloride,TTP-488

Cat No.	Product Name	Synonyms	Targets
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
T3S0208	Hederagenin 28-O-beta-D-glucopyranosyl ester	Hederagenin-28-beta-D-glucopyranoside	Others
	Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage.		Others
TN7020	Astragenol		Others
	Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research.		Others
T3039	Hederagenin	Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol	Others
	Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.		Others
T38499	κ-Carrageenan
	κ-Carrageenan, a natural polymer found predominantly in red seaweeds, can serve as an effective drug carrier for delivering curcumin to cancer cells and inducing apoptosis. Additionally, κ-Carrageenan holds promise as a ...
T83345	3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester
	Hederagenin 28-O-{β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester}3-O-{α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} is a saponin known for its antitumor and anti-inflammatory properties [1].
T78497	λ-Carrageenan
	λ-Carrageenan, a seaweed-derived polysaccharide, is commonly utilized as a proinflammatory agent in basic research and has also been identified as a potent antitumor agent [1].
TN5996	1-Oxohederagenin	3β,23-Dihydroxy-1-oxo-olean-12-en-28-oic acid
	1-Oxohederagenin is a natural product for research related to life sciences. The catalog number is TN5996 and the CAS number is 618390-67-3.
T5716	4'-Methoxyresveratrol	4'-O-Methylresveratrol	advanced glycation end products
	4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced...		advanced glycation end products
T4786	D-Ribose(mixture of isomers)	D-Ribose,D-(-)-Ribose	Others , Endogenous Metabolite
	D-Ribose(mixture of isomers) (D-(-)-Ribose), commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential nutrient because it can be synthesized by almost every tiss...		Others , Endogenous Metabolite

Natural Products

Cycloastragenol

T5575

Synonym: Cyclogalegenol,Astramembrangenin

Target: Epigenetic Reader Domain, Telomerase

Hederagenin 28-O-beta-D-glucopyranosyl ester

T3S0208

Synonym: Hederagenin-28-beta-D-glucopyranoside

Synonym: Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol

3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester

Synonym: 3β,23-Dihydroxy-1-oxo-olean-12-en-28-oic acid

Target:

4'-Methoxyresveratrol

T5716

Synonym: 4'-O-Methylresveratrol

Target: advanced glycation end products

D-Ribose(mixture of isomers)

T4786

Synonym: D-Ribose,D-(-)-Ribose

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02881	RAGE Protein, Human, Recombinant	Human	HEK293 Cells
	RAGE Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35 kDa and the accession number is A0A1U9X785.
TMPY-02927	RAGE Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RAGE Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is A0A1U9X785.
TMPY-01716	RAGE Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RAGE Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is A0A1U9X785.
TMPY-01675	RAGE Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	RAGE Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.3 kDa and the accession number is Q62151-1.
TMPK-00479	AGER Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical ...