Search Result

Search Results for " prl "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T22136	PRL-3 Inhibitor I	PRL-3 Inhibitor,BR-1	Phosphatase , Others
	PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.		Phosphatase , Others
T76594	PRL 2915
	PRL 2915 is a potent antagonist of the human somatostatin subtype 2 receptor (hsst 2), exhibiting a binding affinity (K_i) of 12 nM [1].
T76596	PRL 3195
	PRL 3195 is a somatostatin receptor antagonist, exhibiting K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5 , sst 2 , sst 3 , sst 1 , and sst 4, respectively [1].
T36404L	PRLX-93936 HCL	PRLX-93936 hcl(903499-49-0 Free base)	Ferroptosis , Reactive Oxygen Species
	PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.		Ferroptosis , Reactive Oxygen Species
T36404	PRLX-93936
	PRLX-93936 is an analog of erastin that has antitumor activity. It inhibits the hypoxia-inducible factor 1 (HIF-1) signaling pathway under hypoxic conditions (IC50 = 0.09 μM in a cell-based reporter assay). PRLX-93936 (1...
T27499	GSK-A1		HCV Protease , PI4K
	GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.		HCV Protease , PI4K
T13146	Thienopyridone		Others
	Thienopyridone is a potent and selective inhibitor of phosphatase of regenerating liver (PRL) phosphatase(IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively), and induces p130Cas cleavage and ap...		Others
T25228	CG-707	CG 707
	CG-707 is an inhibitor of PRL-3 that acts by blocking the migration and invasion of metastatic cancer cells.
T80114	FA-Ala-Arg		Endogenous Metabolite
	FA-Ala-Arg is a dipeptide featuring a furylacryloyl group that degrades to yield arginine. It augments nitric oxide (NO) synthesis in MCF-7 cells through a mechanism in which cell-surface Carboxypeptidase-D (CPD) elevate...		Endogenous Metabolite
T81598	Org OD 02-0	10-Ethenyl-19-norprogesterone	p38 MAPK
	10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate MAPK activity, and inhibit prolactin (PRL) secretion in the pi...		p38 MAPK
TP1532	γ-2-MSH (41-58), amide
	Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cel...

Compounds

PRL-3 Inhibitor I

T22136

Synonym: PRL-3 Inhibitor,BR-1

Target: Phosphatase, Others

Synonym: PRLX-93936 hcl(903499-49-0 Free base)

Target: Ferroptosis, Reactive Oxygen Species

Target: HCV Protease, PI4K

Target: Endogenous Metabolite

Org OD 02-0

T81598

Synonym: 10-Ethenyl-19-norprogesterone

Target: p38 MAPK

γ-2-MSH (41-58), amide

TP1532

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00738	PRL Protein, Human, Recombinant	Human	E. coli
	PRL Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25 KDa and the accession number is P01236.
TMPJ-00739	PRL Protein, Sheep, Recombinant (His)	Sheep	HEK293 Cells
	PRL Protein, Sheep, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-30 KDa and the accession number is P01240.
TMPK-00742	PRL-3/PTP4A3 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) pla...
TMPK-01132	PRL-1/PTP4A1 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is ...
TMPJ-00053	PRL-2 Protein, Human, Recombinant (His)	Human	E. coli
	PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ...
TMPK-01375	PRLR Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPK-00547	PRLR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPY-04507	PRL-2A1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PRL-2A1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is A0A0M5HDY8.
TMPJ-00346	PRLR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	PRLR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is Q08501.
TMPJ-00347	PRLR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PRLR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 33-40 KDa and the accession number is Q08501.
TMPY-02386	PTP4A2 Protein, Human, Recombinant (GST)	Human	E. coli
	PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PR...
TMPY-01116	SMR3B Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SMR3B Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.2 kDa and the accession number is P02814.
TMPY-03807	SMR3B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SMR3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 7.3 kDa and the accession number is P02814.
TMPY-04537	PRL8A4 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PRL8A4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is P33580.