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Search Results for " pgf2α "

20

Compounds

Cat No. Product Name Synonyms Targets
T15133 Dinoprost Prostaglandin F2a,PGF Endogenous Metabolite
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.
T20939 Bimatoprost acid 17-phenyl trinor PGF,17-phenyl trinor Prostaglandin F GPR
Bimatoprost acid (17-phenyl trinor PGF) is a metabolically stable analog of PGF and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF for binding to the FP...
T22285 Carboprost 15(S)-15-Methyl Prostaglandin F,15-Methyl-PGF Prostaglandin Receptor
Carboprost (15(S)-15-Methyl Prostaglandin F) is a synthetic prostaglandin analogue of PGF which has the effect of oxytocic. Carboprost is commonly used to restore uterine tone.
T4546 Dinoprost tromethamine salt Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF THAM,Dinolytic,Prostaglandin F THAM Apoptosis , Endogenous Metabolite , Prostaglandin Receptor , Autophagy , PROTAC Linker
Dinoprost tromethamine salt (PGF THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
T30452 Bimatoprost isopropyl ester 17-phenyl trinor PGF-iPr,17-phenyl trinor PGF isopropyl ester
Bimatoprost isopropyl ester is an F-series prostaglandin analog, which has been approved as a hypotensive drug.
T21965 MBCQ PDE
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
T29725 AGN-191129 AGN191129,Prostaglandin F alcohol methyl ether,PGF-OMe,UNII-NK1168QB5T
AGN-191129, also known as Prostaglandin F alcohol methyl ether (PGF-OMe), is an analog of PGF in which the C-1 carboxyl group has been replaced by an O-methyl ether. The compound is reported to retain ocular hypote...
T37991 15-keto Prostaglandin F 15-keto Prostaglandin F,15-keto PGF Endogenous Metabolite , Prostaglandin Receptor
15-keto Prostaglandin F is a metabolite of Prostaglandin F that lowers intraocular pressure in rabbits.
T36146 13,14-dihydro Prostaglandin F 13,14-dihydro Prostaglandin F,13,14-dihydro PGF
13,14-dihydro Prostaglandin F (13,14-dihydro PGF) is the analog of PGF which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF. The ED50 value...
T37326 Prostaglandin F 1,11-lactone Prostaglandin F 1,11-lactone,PGF 1,11-lactone Prostaglandin Receptor
Prostaglandin F 1,11-lactone (PGF 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F and can be used in studies about treating glaucoma. Prostaglandin F 1,11-lactone is active as an antifertility agent w...
T36619 Aligeron Prostaglandin Receptor
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit PGF-induced diarrhea in mice and PGE2-induced paw edema in...
TQ0203 Tafluprost MK2452,AFP-168 Prostaglandin Receptor
Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF.
T10960L Darbufelone mesylate CI-1004 mesylate Prostaglandin Receptor , LTR
Darbufelone mesylate (CI-1004 mesylate) inhibited PGF and LTB4 in cells. Darbufelone mesylate inhibited PGHS-2 with IC50 value of 0.19 μM and PGHS-1 with IC50 value of 20 μM.
T10381 AS2717638 Others
AS2717638 is an orally active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist (IC50: 38 nM for hLPA5). It also significantly improves PGF-, PGE2-, and AMPA-induced allodynia.
T12285 Ebopiprant OBE022,OBE-022 Others
Ebopiprant (OBE022) is an orally available, selective and potent prostaglandin F (PGF) receptor antagonist that interferes with the binding of PGF0126α to the FPR and can be used in the study of obesity.
T10960 Darbufelone CI-1004 Prostaglandin Receptor , LTR
Darbufelone (CI-1004) is a non-competitive dual inhibitor of PGF and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.
T5847 Cloprostenol sodium salt ICI 80996 sodium salt,DL-Cloprostenol sodium,Cloprostenol sodium Prostaglandin Receptor
Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water solute, crystalline form of cloprostenol than the free acid, is a synthetic analog of prostaglandin F.
T37327 Prostaglandin F 1,15-lactone Prostaglandin F 1,15-lactone
PGF 1,15-lactone is a lipid-soluble internal ester of PGF. Hydrolysis of the lactone readily produces free PGF in plasma. In rhesus monkeys, a total dose of 15 mg of PGF 1,15-lactone terminates early pregnancy, w...
T37995 16-phenoxy tetranor Prostaglandin F 16-phenoxy tetranor Prostaglandin F
16-phenoxy PGF is a metabolically stable analog of PGF. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF.
T38196 Prostaglandin F isopropyl ester Prostaglandin F isopropyl ester
PGF isopropyl ester is an ester prodrug of PGF with enhanced lipid solubility. Due to better membrane penetration, PGF isopropyl ester is more suitable than PGF or PGF tromethamine salt for topical application ...

Compounds

Dinoprost
T15133
Synonym: Prostaglandin F2a,PGF
Target: Endogenous Metabolite
Bimatoprost acid
T20939
Synonym: 17-phenyl trinor PGF,17-phenyl trinor Prostaglandin F
Target: GPR
Carboprost
T22285
Synonym: 15(S)-15-Methyl Prostaglandin F,15-Methyl-PGF
Target: Prostaglandin Receptor
Dinoprost tromethamine salt
T4546
Synonym: Dinoprost Tromethamine,Zinoprost,Prostin F2 alpha,PGF THAM,Dinolytic,Prostaglandin F THAM
Target: Apoptosis, Endogenous Metabolite, Prostaglandin Receptor, Autophagy, PROTAC Linker
Bimatoprost isopropyl ester
T30452
Synonym: 17-phenyl trinor PGF-iPr,17-phenyl trinor PGF isopropyl ester
Target:
MBCQ
T21965
Synonym:
Target: PDE
AGN-191129
T29725
Synonym: AGN191129,Prostaglandin F alcohol methyl ether,PGF-OMe,UNII-NK1168QB5T
Target:
15-keto Prostaglandin F
T37991
Synonym: 15-keto Prostaglandin F,15-keto PGF
Target: Endogenous Metabolite, Prostaglandin Receptor
13,14-dihydro Prostaglandin F
T36146
Synonym: 13,14-dihydro Prostaglandin F,13,14-dihydro PGF
Target:
Prostaglandin F 1,11-lactone
T37326
Synonym: Prostaglandin F 1,11-lactone,PGF 1,11-lactone
Target: Prostaglandin Receptor
Aligeron
T36619
Synonym:
Target: Prostaglandin Receptor
Tafluprost
TQ0203
Synonym: MK2452,AFP-168
Target: Prostaglandin Receptor
Darbufelone mesylate
T10960L
Synonym: CI-1004 mesylate
Target: Prostaglandin Receptor, LTR
AS2717638
T10381
Synonym:
Target: Others
Ebopiprant
T12285
Synonym: OBE022,OBE-022
Target: Others
Darbufelone
T10960
Synonym: CI-1004
Target: Prostaglandin Receptor, LTR
Cloprostenol sodium salt
T5847
Synonym: ICI 80996 sodium salt,DL-Cloprostenol sodium,Cloprostenol sodium
Target: Prostaglandin Receptor
Prostaglandin F 1,15-lactone
T37327
Synonym: Prostaglandin F 1,15-lactone
Target:
16-phenoxy tetranor Prostaglandin F
T37995
Synonym: 16-phenoxy tetranor Prostaglandin F
Target:
Prostaglandin F isopropyl ester
T38196
Synonym: Prostaglandin F isopropyl ester
Target:
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TargetMol