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15-keto Prostaglandin F2α

Catalog No. T37991 CAS 35850-13-6

Synonyms: 15-keto Prostaglandin F2α, 15-keto PGF2α

15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.

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15-keto Prostaglandin F2α Chemical Structure

15-keto Prostaglandin F2α, CAS 35850-13-6

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.
In vivo	15-keto Prostaglandin F2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively.[1] [2] 15-keto Prostaglandin F2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.[3]

Synonyms	15-keto Prostaglandin F2α, 15-keto PGF2α
Molecular Weight	352.47
Formula	C20H32O5
CAS No.	35850-13-6

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: 100 mg/mL (from PGF2a)

Ethanol: 100 mg/mL (from PGF2a)

DMSO: 100 mg/mL (from PGF2a)

References and Literature

1. Sorensen PW, et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol. Reprod. 39(5), 1039-1050 (1988). 2. Moore A, et al. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol. 199(Pt 10), 2307-2316 (1996). 3. Woodward DF, et al. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res. 1989;21(6),428-435.

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Keywords

15-keto Prostaglandin F2α 35850-13-6 GPCR/G Protein Immunology/Inflammation Metabolism Prostaglandin Receptor Endogenous Metabolite 15-keto Prostaglandin F2a 15-keto Prostaglandin F2alpha 15-keto PGF2alpha 15-keto PGF2α 15-keto PGF2a inhibitor inhibit

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