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Prostaglandin F2α 1,11-lactone

Catalog No. T37326 CAS 62410-84-8

Synonyms: Prostaglandin F2α 1,11-lactone, PGF2α 1,11-lactone

Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.

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Prostaglandin F2α 1,11-lactone Chemical Structure

Prostaglandin F2α 1,11-lactone, CAS 62410-84-8

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10 mg	35 days	$ 1,700.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Prostaglandin F2α 1,11-lactone, PGF2α 1,11-lactone
Molecular Weight	336.47
Formula	C20H32O4
CAS No.	62410-84-8

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

PBS (pH 7.2): <50 μg/mL

Ethanol:PBS (30:70): 8 mg/mL

DMSO: 9mg/mL (26.7mM)

Ethanol: >100 mg/mL

DMF: >20 mg/mL

References and Literature

1. Chien DS, Tang-Liu DD, Woodward DF. Ocular penetration and bioconversion of prostaglandin F2alpha prodrugs in rabbit cornea and conjunctiva. J Pharm Sci. 1997 Oct;86(10):1180-6. 2. Woodward DF, et al. Studies on the ocular hypotensive effects of prostaglandin F2 alpha ester prodrugs and receptor selective prostaglandin analogs. J Ocul Pharmacol. 1994 Spring;10(1):177-93.

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Keywords

Prostaglandin F2α 1,11-lactone 62410-84-8 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor Prostaglandin F2a 1,11-lactone Prostaglandin F2alpha 1,11-lactone PGF2alpha 1,11-lactone PGF2α 1,11-lactone PGF2a 1,11-lactone inhibitor inhibit

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