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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38737L | SDKPDMAEIEKFDKSK acetate | SDKPDMAEIEKFDKSK acetate(1339864-27-5 free base) | Others |
SDKPDMAEIEKFDKSK acetate is a thymosin β4 derivative. Thymosin β4 inhibits PDGF-BB-induced fibrogenesis, proliferation and migration of HSC by blocking Akt phosphorylation. | |||
T67442 | CGP-53716 | ||
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i... | |||
T83661 | 17(R,S)-Benzo-Resolvin D1 | 17(R,S)-Benzo-RvD1,Benzo-RvD1 | |
Benzo-resolvin D1 (benzo-RvD1), a derivative of the specialized pro-resolving mediator (SPM) RvD1, effectively reduces PDGF-BB-induced cytoskeletal alterations and PDGF-triggered migration in isolated human vascular smoo... | |||
T36547 | Quazinone | ||
Quazinone is a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilating properties.1,2 It induces relaxation of precontracted isolated human cavernous smooth muscle (IC50 = 4.2 μM).1 Qua... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6S0655 | Corynoxeine | ERK | |
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty. | |||
TN2354 | Methylnissolin | 3-Hydroxy-9,10-dimethoxyptercarpan | ERK , PDGFR |
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects. | |||
TN2063 | Physalin B | NSC-287088 | Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD |
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel... | |||
T2734 | Sennoside B | PDGFR | |
Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00735 | PDGF-BB Protein, Human, Recombinant | Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-01996 | SorCS1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
VPS1 domain-containing receptor SorCS1, also known as SORCS1 and SORCS, is a single-pass type I membrane protein that belongs to the SORCS family and SORCS1 subfamily. SORCS1 contains five BNR repeats and one PKD domain.... |