paca — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T33858	PACA	N-Propargyl Caffeamide
	PACA, (N-propargyl Caffeamide)enhances NGF-induced neurite growth and reduces 6-hydroxydopamine neurotoxicity in neuron cultures. Parkinson's disease (PD) is associated with insufficient production of nerve growth factor...
T4671	BN82002	CDC25 Phosphatase Inhibitor I	Phosphatase
	BN82002 (CDC25 Phosphatase Inhibitor I) is a synthetic inhibitor of CDC25 phophatases		Phosphatase
T60028	MM41		DNA/RNA Synthesis
	MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.		DNA/RNA Synthesis
T7610	GW284543	UNC10225170	MEK
	GW284543 (UNC10225170) is a selective inhibitor of MEK5 .		MEK
T11898	LXH254		Raf
	LXH254 is a potent C-Raf and B-Raf inhibitor.		Raf
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
TP1722L	PACAP (6-38), human, ovine, rat acetate		PACAP
	PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.		PACAP
TP1878L	PACAP 1-38 acetate		PACAP
	PACAP 1-38 acetate is a pituitary adenylate cyclase activating polypeptide (PACAP) analogue. PACAP 1-38 acetate binds to PACAP type I receptor(IC50 = 4 nM) and PACAP type II VIP2 receptor(IC50 = 1 nM) but not to PACAP ty...		PACAP
TP1070L	PACAP (1-27), human, ovine, rat acetate	PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)	PACAP
	PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.		PACAP
TP1618L	PACAP-38 (31-38), human, mouse, rat acetate	PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)	PACAP
	PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY an...		PACAP
T3548	Epacadostat	INCB 024360,IDO Inhibitor 1	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
TP1878	PACAP (1-38), human, ovine, rat	Pituitary Adenylate Cyclase Activating Polypeptide 38,PACAP 1-38	PACAP
	PACAP (1-38), human, ovine, rat (Pituitary Adenylate Cyclase Activating Polypeptide 38) is a neuropeptide with 38 amino acid residues.		PACAP
TP1054	PACAP (1-38), human, ovine, rat TFA	Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP...
T83510	[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2	BM-PACAP
	[Arg-15,-20,-21, Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic analogue of PACAP 1-27 that exhibits a relaxant effect [1].
TP1850	PACAP-Related Peptide (PRP), human
	PACAP-Related Peptide (PRP), human,a 29 amino-acid region of the PACAP precursor protein, is synthesized in quantities sufficient for biological and structural studies.
T81571	PACAP (1-38) free acid TFA
	PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin secretion and promoting the release of vasoactive intestinal...
T77127	Pacanalotamab
	Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) that specifically targets BCMA (B cell maturation antigen) and CD3ɛ. By redirecting T cells to cells expressing BCMA on their surface, Pacanalotama...
T37435	PACAP-related Peptide (rat) (trifluoroacetate salt)		PACAP
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny...		PACAP
T36428	PACAP-related Peptide (human) (trifluoroacetate salt)		PACAP
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny...		PACAP
TP1722	PACAP (6-38), human, ovine, rat
	PACAP (6-38), human, ovine, rat is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase.