pac — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T18514	PAC		Others
	PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC...		Others
T2503	PAC-1	Procaspase activating compound 1	Apoptosis , Caspase , Autophagy
	PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.		Apoptosis , Caspase , Autophagy
T37139	5'-O-DMT-PAC-dA
	5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1]. [1]. Schulhof JC, et, al. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile...
T18603	PROTAC BRD4 degrader for PAC-1		Others
	PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective pro...		Others
T16426	Asivatrep	PAC-14028	Others
	Asivatrep is an effective and selective transient receptor potential vanilloid type I antagonist.		Others
T74121	DMT-dA(PAc) Phosphoramidite
	DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite suitable for DNA or RNA synthesis applications.
TNU1202	3’,5’-TIPS-N-PAc-Guanosine
	3',5'-TIPS-N-PAc-Guanosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
T27635	Isoxepac	Olopatadine USP Related Compound C	Others
	Isoxepac (Olopatadine USP Related Compound C) is a non-steroidal anti-antiphlogistic agent and analgesic.		Others
T32570	Lappaconine	20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine	Others
	Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids.		Others
TP1070L	PACAP (1-27), human, ovine, rat acetate	PACAP 1-27 acetate,PACAP (1-27), human, ovine, rat acetate(127317-03-7 free base)	PACAP
	PACAP (1-27), human, ovine, rat acetate (PACAP 1-27 acetate) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.		PACAP
TP1722L	PACAP (6-38), human, ovine, rat acetate		PACAP
	PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively.		PACAP
T78105	PAC1R antagonist 1		PACAP
	PAC1R antagonist 1 is an orally active PAC1 receptor antagonist that inhibits abnormal pain induced by pituitary adenylate cyclase-activating polypeptide (PACAP) and nerve damage, and may be used in the study of neoplasm...		PACAP
TP1878L	PACAP 1-38 acetate		PACAP
	PACAP 1-38 acetate is a pituitary adenylate cyclase activating polypeptide (PACAP) analogue. PACAP 1-38 acetate binds to PACAP type I receptor(IC50 = 4 nM) and PACAP type II VIP2 receptor(IC50 = 1 nM) but not to PACAP ty...		PACAP
TN1754	Hypaconine		Others
	Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. It exhibits strong cardiac activity.		Others
TQ0245	Sapacitabine	CS682,CYC682	Nucleoside Antimetabolite/Analog
	Sapacitabine is a nucleoside analog prodrug with antitumor activity.		Nucleoside Antimetabolite/Analog
T38815	Millepachine		Apoptosis
	Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.		Apoptosis
T5749	10-Deacetyl-7-xylosyl paclitaxel	10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside	Others , Microtubule Associated
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.		Others , Microtubule Associated
T6S1884	Benzoylhypaconine	Benzoylhypacoitine	Others
	Benzoylhypaconine (Benzoylhypacoitine) might be the principal active components which affect mitochondrial growth by Fuzi and its processed products.		Others
T21907	PACOCF3	1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone	Phospholipase
	PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2]...		Phospholipase
TP1618L	PACAP-38 (31-38), human, mouse, rat acetate	PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)	PACAP
	PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY an...		PACAP