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Search Results for " ogd "

Targets

11

Compounds

3

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6651 Safinamide mesylate PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate MAO , Monoamine Oxidase
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T25450 GGTI 2147 GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147 NF-κB , Rho
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
T14912 CD3254 Retinoid Receptor
CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
T13920L Terlipressin Acetate Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous Vasopressin Receptor
Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in...
T3560 Desmethylanethol trithione ADT-OH VEGFR , Akt
Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly...
T60528 PDPOB
PDPOB is a phenyl carboxylic acid derivative with the potential to be used in the study of cerebral ischemia. PDPOB is shown to be protective against OGD/R-evoked multi-aspect neuronal deterioration in SH-SY5Y cells, as ...
T83043 Anti-MI/R injury agent 1
Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R) injury. It improves cell viability in cardiomyocytes subjec...
T80420 TAT-NEP1-40 acetate Apoptosis
TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose deprivation (OGD) and encourages neurite outgrowth. This compound al...
T80418 TAT-NEP1-40 Apoptosis
TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promoting neurite outgrowth. Furthermore, it enhances neurologic outcomes po...
T80419 TAT-NEP1-40 TFA Apoptosis
TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth. Additionally, it enhances neurological outcomes post-ischemia by...
T36570 KUS121
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, ...
Cat No. Product Name Synonyms Targets
TN1957 Mulberrofuran Q MulberrofuranQ
Mulberrofuran Q is an active compound that inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase product) , which protects neuronal cells from hypoxia-glycorrhoea-def...
T6S1740 Nardosinone Others
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...
TN4168 Grifolin Others
Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proli...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06034 FGFR1 Protein, Human, Recombinant (beta (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPH-00850 OGDC-E1 Protein, Human, Recombinant (His & SUMO) Human E. coli
2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall c...
TMPH-00667 OGDC-E2 Protein, E. coli O157:H7, Recombinant (His) E. coli E. coli
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
TMPH-02475 OGDC-E Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall c...
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