Search Result

Search Results for " nsp "

Targets

Monoamine Transporter Na-K-Cl cotransporter Monocarboxylate transporter transporter Serotonin Transporter PDE

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T12267	NSP-805		PDE
	NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.		PDE
T19040	NSP-SA-NHS		Others
	NSP-SA-NHS is a chemiluminescent acridinium ester that can be used for immunoassays.		Others
T16985	Tanaproget	NSP-989	Others
	Tanaproget is a novel nonsteroidal progesterone receptor agonist which can bind to the PR from various species with a higher relative affinity than reference steroidal progestins (IC50: 0.1 nM),		Others
T0383	Fenspiride hydrochloride	Fenspiride HCl,Pneumorel,Fluiden,Decaspiride	Adrenergic Receptor , PDE , Histamine Receptor
	Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ...		Adrenergic Receptor , PDE , Histamine Receptor
T60271	SARS-CoV-2 nsp3-IN-2
	SARS-CoV-2 nsp3-IN-2 is a SARS-CoV-2 nsp3 macrodomain (Mac1) inhibitor with IC 50 value of 180 μM. SARS-CoV-2 nsp3 macrodomain is an ADP-ribosylhydrolase that is critical for coronavirus replication and pathogenesis. SAR...
T81962	Lactate transportor 1		Monocarboxylate transporter
	Lactate Transporter 1 (Compound 1) serves as an active lactate transporter within living cells and exerts cytotoxic effects, exhibiting IC50 values of 3.36 μM in HeLa, 3.27 μM in CAL27, 5.58 μM in MCF7, and 7.66 μM in MC...		Monocarboxylate transporter
T60861	SARS-CoV-2 nsp3-IN-1
	SARS-CoV-2 nsp3-IN-1 (Compound 15c) shows significant selectivity for coronavirus macrodomains, especially SARS-CoV-2 Mac1. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity that is an inhibitor of Mac1...
T71141	Fenspiride-d5
	Fenspiride-d5 is intended for use as an internal standard for the quantification of fenspiride by GC- or LC-MS. Fenspiride is an antagonist of histamine H1 receptors and a non-steroidal anti-inflammatory drug (NSAID). It...
T79526	SARS-CoV-2 nsp14-IN-4		SARS-CoV
	SARS-CoV-2 nsp14-IN-4 (Compound 12q), a non-cytotoxic and cell-permeable inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50 = 19 nM), is employed in COVID-19 research [1].		SARS-CoV
T62413	SARS-CoV-2 nsp13-IN-1
	SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent inhibitor of nsp13 (non-structural protein 13). SARS-CoV-2 nsp13-IN-1 inhibits only nsp13 ssDNA+ATPase (IC50: 6 μM), but not ssDNA-ATPase. CoV-2 nsp13-IN-1 was able to be u...
T60417	Fenspiride
	Fenspiride is an antagonist of H1-histamine receptors. Fenspiride is an orally active non-steroidal anti-inflammatory agent that can be used for the treatment of respiratory tract infections and otitis media. Fenspiride ...
T62829	SARS-CoV-2 nsp14-IN-1
	SARS-CoV-2 nsp14-IN-1 (Compound 3) is a typical dual-substrate inhibitor of SARS-CoV-2Nsp14 Mtase (IC50: 0.061 μM). Histone lysine, protein arginine, DNA and RNA, etc.).
T62375	SARS-CoV-2 nsp13-IN-3
	SARS-CoV-2 nsp13-IN-3 (Compound C3) is a small molecule inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on nsp13 ssDNA+ATPase (IC50: 32 μM).
T35059	VinSpinIC	Vinnie's Spindlin Inactive Control,TD020826a
	VinSpinIC is an inactive control for VinSpinIn.
T125993	Schisansphenin B
	Schisansphenin B is a useful organic compound for research related to life sciences. The catalog number is T125993 and the CAS number is 1357469-93-2.
T62031	SARS-CoV-2 nsp13-IN-4
	SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective small-molecule inhibitor of nsp13 helicase. SARS-CoV-2 nsp13-IN-4 inhibits the ssDNA+ ATPase activity of nsp13 with an IC 50 of 57 μM. SARS-CoV-2 nsp13-IN-4 can pr...
T126361	Epidanshenspiroketallactone
	Epidanshenspiroketallactone is a useful organic compound for research related to life sciences and the catalog number is T126361.
T35060	VinSpinIn	Vinnie's Spindlin Inhibitor,TD020824a
	VinSpinIn is a probe for the Spin family proteins.
T62248	SARS-CoV-2 nsp13-IN-6
	SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on ssDNA+ATPase (IC50: 27 μM) and ssDNA-ATPase (IC50: 33 μM). nsp13-IN-6 can be used in anti-COVID-19 st...
T62819	SARS-CoV-2 nsp14-IN-2
	SARS-CoV-2 nsp14-IN-2 is a potent inhibitor of SARS-CoV-2 Nsp14 methyltransferase (IC50: 0.093 μM). SARS-CoV-2 nsp14-IN-2 has the potential to be used in COVID-19 studies.
T126549	Danshinspiroketallactone
	Danshinspiroketallactone is a useful organic compound for research related to life sciences and the catalog number is T126549.
T78725	SARS-CoV-2 nsp14-IN-3		SARS-CoV
	SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor targeting the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value of 3.5 μM [1].		SARS-CoV
TP1849	Transportan
	Transportan is a 27 amino acid-long peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine.
T62264	SARS-CoV-2 nsp13-IN-2
	SARS-CoV-2 nsp13-IN-2 (Compound C2) is a small molecule inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on nsp13 ssDNA+ATPase (IC50: 42 μM).
T63615	SARS-CoV-2 nsp13-IN-5
	SARS-CoV-2 nsp13-IN-5 is a potent inhibitor of SARS-CoV-2 nsp13, capable of acting on ssDNA+ATPase (IC50: 50 μM) and ssDNA-ATPase (IC50: 55 μM). SARS-CoV-2 nsp13-IN-5 can be used in anti-COVID-19 studies.
T62494	Cathepsin C-IN-5
	Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S,...

Compounds

Fenspiride hydrochloride

T0383

Synonym: Fenspiride HCl,Pneumorel,Fluiden,Decaspiride

Target: Adrenergic Receptor, PDE, Histamine Receptor

SARS-CoV-2 nsp3-IN-2

T60271

Synonym:

Target:

Lactate transportor 1

T81962

Synonym:

Target: Monocarboxylate transporter

SARS-CoV-2 nsp3-IN-1

SARS-CoV-2 nsp14-IN-4

T79526

Synonym:

Target: SARS-CoV

SARS-CoV-2 nsp13-IN-1

SARS-CoV-2 nsp14-IN-1

T62829

Synonym:

Target:

SARS-CoV-2 nsp13-IN-3

Synonym: Vinnie's Spindlin Inactive Control,TD020826a

SARS-CoV-2 nsp13-IN-4

T62031

Synonym:

Target:

Epidanshenspiroketallactone

Synonym: Vinnie's Spindlin Inhibitor,TD020824a

Target:

SARS-CoV-2 nsp13-IN-6

T62248

Synonym:

Target:

SARS-CoV-2 nsp14-IN-2

T62819

Synonym:

Target:

Danshinspiroketallactone

T126549

Synonym:

Target:

SARS-CoV-2 nsp14-IN-3

SARS-CoV-2 nsp13-IN-2

T62264

Synonym:

Target:

SARS-CoV-2 nsp13-IN-5

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02001	RTN4 Protein, Human, Recombinant (GST)	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPJ-01425	SARS-CoV-2 NSP1 Protein (His)	SARS-CoV-2	E. coli
	The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, po...
TMPH-03489	SARS-CoV-2 3C-like proteinase NSP5 Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 3C-like proteinase NSP5 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 39.8 kDa and the accession number is YP_009725301.1.
TMPH-03490	SARS-CoV-2 Non-structural protein 3/NSP3 Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Non-structural protein 3/NSP3 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 41.7 kDa and the accession number is YP_009725299.1.
TMPY-05749	SARS-CoV-2 NSP8 Protein (Avi)	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPH-03492	SARS-CoV-2 Non-structural protein 9/NSP9 Protein (Flag & hFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Non-structural protein 9/NSP9 Protein (Flag & hFc) is expressed in HEK293 mammalian cells with C-hFC-Flag tag. The predicted molecular weight is 44.5 kDa and the accession number is P0DTD1 YP_009742616.1.
TMPY-06012	SARS-CoV-2 NSP10 Protein	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp...
TMPY-06009	SARS-CoV-2 NSP7 Protein	SARS-CoV-2	E. coli
	NSP7 is conserved within the coronaviridae. NSP7 is a component of the coronavirus replicase polyprotein to comprise a repilication complex. NSP7 has been shown to interact with NSP10 and NSP1 which indicate that NSP7 ha...
TMPJ-01426	SARS-CoV-2 NSP2 Protein (His)	SARS-CoV-2	E. coli
	The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins i...
TMPY-05820	SARS-CoV-2 NSP3 Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 NSP3 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 19.87 kDa and the accession number is YP_009725299.1.
TMPH-00206	Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO)	Bordetella pertussis	E. coli
	Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping c...
TMPJ-01428	SARS-CoV-2 NSP8 Protein (His)	SARS-CoV-2	E. coli
	Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are...
TMPY-06011	SARS-CoV-2 NSP10 Protein (His)	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp...
TMPH-03491	SARS-CoV-2 Non-structural protein 9/NSP9 Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Non-structural protein 9/NSP9 Protein (His) is expressed in E. coli.
TMPJ-01427	SARS-CoV-2 NSP7 Protein (His)	SARS-CoV-2	E. coli
	The ∼30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are...
TMPY-06416	SARS-CoV-2 NSP8 Protein	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPY-05712	SARS-CoV-2 NSP9 Protein (His & Avi)	SARS-CoV-2	E. coli
	SARS-CoV-2 NSP9 Protein (His & Avi) is expressed in E. coli expression system. The predicted molecular weight is 15.46 kDa and the accession number is YP_009725305.1.
TMPJ-01429	SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)	SARS-CoV-2	E. coli
	The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds...