napa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3575	Acecainide hydrochloride	ASL 601,NAPA	Others
	Acecainide hydrochloride (NAPA) is a major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.		Others
T0249	N-Acetylprocainamide	NAPA,Acecainide	Potassium Channel , Sodium Channel , Drug Metabolite
	N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.		Potassium Channel , Sodium Channel , Drug Metabolite
T7587	Tenapanor	RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722	Sodium Channel
	Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinica...		Sodium Channel
T6763	Xevinapant	ARRY-334543,SM-406,AT406,Debio-1143	IAP
	Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ...		IAP
T0113	Mebhydrolin napadisylate	Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline	5-HT Receptor , AChR , Histamine Receptor
	Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.		5-HT Receptor , AChR , Histamine Receptor
T9593	Senaparib	IMP4297	PARP
	Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.		PARP
T16802	Lonapalene	RS4317	Others
	Lonapalene is a topically effective inhibitor of 5-lipoxygenase.		Others
TN2281	Sinapaldehyde	trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde	Antibacterial
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ...		Antibacterial
T3218	Napabucasin	BBI608	STAT
	Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.		STAT
T60097	Methyl (E)-sinapate		Others
	Methyl (E)-sinapate is isolated from the Polygala sibirica L.var. megalopha Fr.		Others
T6007	Birinapant	TL32711	Apoptosis , IAP , HIV Protease
	Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with po...		Apoptosis , IAP , HIV Protease
TN1929	Methyl sinapate		Others
	Methyl sinapate can increase the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.		Others
T40572	Lesogaberan napadisylate	AZD-3355 napadisylate
	Lesogaberan (AZD-3355) napadisylate is a potent and selective agonist of GABA B receptors, with an EC 50 of 8.6 nM for human recombinant GABA B receptors. It demonstrates an affinity (Ki) of 5.1 nM for rat GABA B recepto...
T35940	Darinaparsin	Dimethylarsinic glutathione,Darinaparsin
	Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 µM) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 µM)...
T26553	Aclatonium Napadisilate	Acaltonium napadisilate
	Aclatonium Napadisilate, a cholinergic agonist, has been shown to stimulates endocrine and exocrine pancreatic secretion.
T24995	Abediterol napadisylate	LAS100977 napadisylate
	Abediterol napadisylate is a novel long-acting β2-agonist in persistent asthma that is efficacy, safe, and tolerable.
T13405L	Fanapanel	MPQX,ZK200775	Others
	Fanapanel is a highly selective AMPA/kainate antagonist with little activity against NMDA. It also has Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.		Others
TN5027	Sinapaldehyde glucoside		Others
	Sinapaldehyde glucoside is a natural product of Phellodendron, Rutaceae. The catalog number is TN5027 and the CAS number is 154461-65-1. Sinapaldehyde glucoside can be used as a reference standard.		Others
T70762	Senaparib hydrochloride
	Senaparib hydrochloride is a potent and selective oral PARP1/2 inhibitor with strong antitumor activity.
TN6365	3-Deoxy-11,13-dihydroisosecotanapartholide
	3-Deoxy-11,13-dihydroisosecotanapartholide is a natural product for research related to life sciences. The catalog number is TN6365 and the CAS number is 572924-43-7.