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Search Results for " n-methyltransferase "

20

Compounds

Cat No. Product Name Synonyms Targets
T8548 Metoprine Histone Methyltransferase , Antifolate , Histamine Receptor
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
T8381 Amodiaquine Others , Histone Methyltransferase , Parasite
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
T2038 RG108 N-Phthalyl-L-tryptophan DNA Methyltransferase
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
T2352 AMI-1 Histone Methyltransferase
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).
T7157 XY1 Histone Methyltransferase
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action.
T0381 Amodiaquine dihydrochloride dihydrate Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate Histone Methyltransferase , Parasite , Histamine Receptor
Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.
T22956 LY 78335 1-(2,3-Dichlorophenyl)ethanamine hydrochloride Others
LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.
T10363 Arazine N-Acetyl-S-farnesyl-L-cysteine Others
Arazine (N-Acetyl-S-farnesyl-L-cysteine) can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site. Arazine is a cell-permeable modulator of G protein and G...
T1354 N-Acetyl-5-hydroxytryptamine Normelatonin,O-Demethylmelatonin,N-Acetylserotonin Trk receptor , Endogenous Metabolite
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to m...
T8790 1-Methylhistamine dihydrochloride Endogenous Metabolite
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains...
T8106 JBSNF-000088 JBSNF000088 Others
JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders.
T7697 BIX-01294 Histone Methyltransferase , Autophagy
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
T8760 NNMTi 5-Amino-1-methylquinolinium Others
NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adip...
T1959 BIX-01294 trihydrochloride BIX 01294 Histone Methyltransferase , Autophagy
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.
T72947 JBSNF-000028 JBSNF-000028 free base Others
JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, a...
T4909 N-Acetyl-DL-methionine Others , Endogenous Metabolite
N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species...
T4120 N-Methylsarcosine N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG Endogenous Metabolite
N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of p...
T27924 LY 87130 LY87130,LY-87130
LY 87130 is a phenylethanolamine-N-methyltransferase inhibitor.
T27831 Lifibrate
Lifibrate is an inhibitor of cholinephosphotransferase (CPT), phosphatidyl-N,N-dimethylethanolamine N-methyltransferase (PDE-NMT), and phosphatidyl-N-methylethanolamine N-methyltransferase (PME-NMT).
T23367 SKF 91488 dihydrochloride Others
histamine N-methyltransferase inhibitor

Compounds

Metoprine
T8548
Synonym:
Target: Histone Methyltransferase, Antifolate, Histamine Receptor
Amodiaquine
T8381
Synonym:
Target: Others, Histone Methyltransferase, Parasite
RG108
T2038
Synonym: N-Phthalyl-L-tryptophan
Target: DNA Methyltransferase
AMI-1
T2352
Synonym:
Target: Histone Methyltransferase
XY1
T7157
Synonym:
Target: Histone Methyltransferase
Amodiaquine dihydrochloride dihydrate
T0381
Synonym: Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate
Target: Histone Methyltransferase, Parasite, Histamine Receptor
LY 78335
T22956
Synonym: 1-(2,3-Dichlorophenyl)ethanamine hydrochloride
Target: Others
Arazine
T10363
Synonym: N-Acetyl-S-farnesyl-L-cysteine
Target: Others
N-Acetyl-5-hydroxytryptamine
T1354
Synonym: Normelatonin,O-Demethylmelatonin,N-Acetylserotonin
Target: Trk receptor, Endogenous Metabolite
1-Methylhistamine dihydrochloride
T8790
Synonym:
Target: Endogenous Metabolite
JBSNF-000088
T8106
Synonym: JBSNF000088
Target: Others
BIX-01294
T7697
Synonym:
Target: Histone Methyltransferase, Autophagy
NNMTi
T8760
Synonym: 5-Amino-1-methylquinolinium
Target: Others
BIX-01294 trihydrochloride
T1959
Synonym: BIX 01294
Target: Histone Methyltransferase, Autophagy
JBSNF-000028
T72947
Synonym: JBSNF-000028 free base
Target: Others
N-Acetyl-DL-methionine
T4909
Synonym:
Target: Others, Endogenous Metabolite
N-Methylsarcosine
T4120
Synonym: N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG
Target: Endogenous Metabolite
LY 87130
T27924
Synonym: LY87130,LY-87130
Target:
Lifibrate
T27831
Synonym:
Target:
SKF 91488 dihydrochloride
T23367
Synonym:
Target: Others
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TargetMol