metformin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8526	Metformin	1,1-Dimethylbiguanide	Mitophagy , AMPK , Autophagy
	Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm...		Mitophagy , AMPK , Autophagy
T0740	Metformin hydrochloride	Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride	Mitophagy , AMPK , Autophagy
	Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro...		Mitophagy , AMPK , Autophagy
T73712	Metformin-d6 hydrochloride	1,1-Dimethylbiguanide-d6 hydrochloride	AMPK , Autophagy
	Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuterated form of Metformin that can be used to study Metformin metabolism in vivo, and is often used as an internal standard for Metformin.ccc_R08 can be use...		AMPK , Autophagy
T32758	Linagliptin mixture with metformin	Jentadueto Xr,Linagliptin / metformin,Jentadueto
	Linagliptin mixture with metformin is used for the treatment of type 2 diabetes.
T70806	Metformin icosapent
	Metformin icosapent is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T71222	Metformin glycinate
	Metformin glycinate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T69405	Metformin embonate
	Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T69049	Metformin orotate
	Metformin orotate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T20028	Janumet	Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate
	Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
TN2252	Syrosingopine		Dopamine Receptor
	Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.		Dopamine Receptor
T70804	Itasetron hydrochloride monohydrate
	Itasetron hydrochloride monohydrate is a potent 5HT-3 receptor antagonist.
T8929	BC1618	2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-	Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
	BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp...		Mitophagy , Others , E1/E2/E3 Enzyme , AMPK
T83971L	LCC-12 FA		Antiviral , Antibacterial
	LCC-12 FA is a dimer composed of metformin that induces a decrease in the NAD(H) pool by targeting mitochondrial copper(ii).LCC-12 FA reduces inflammation in mouse models of bacterial and viral infections and may be used...		Antiviral , Antibacterial
T8532	IM156		OXPHOS
	IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in anima...		OXPHOS
T0242	Sitagliptin	MK0431	Proteasome , DPP-4 , Autophagy
	Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedion...		Proteasome , DPP-4 , Autophagy
T11570	HL271		AMPK
	HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.		AMPK
T35532	Galegine hydrochloride
	Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This comp...
T83866	LCC-12 formate
	LCC-12, a derivative of the biguanide metformin, acts as a copper (II) chelator. It efficiently forms a monomeric bond with copper (II) and at 20 µM, it mitigates hydrogen peroxide-induced oxidation from NADH to NAD+. At...