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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2008 | LY294002 | LY 294002,NSC 697286,SF 1101 | Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy |
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 ... | |||
T4079 | LY-294002 hydrochloride | SF 1101,LY 294002,NSC 697286 | PI3K |
LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation... | |||
T4423 | LY 303511 hydrochloride | LY303511 hydrochloride | Potassium Channel , TNF , mTOR |
LY 303511 hydrochloride is a potent mTOR inhibitor | |||
T16875 | SF1126 | Others | |
SF1126 is a relevant pan and dual first-in-class PI3K/BRD4 inhibitor. SF1126 is an RGDS-conjugated LY294002 prodrug, which is designed to exhibit increased solubility and bind to specific integrins within the tumor compa... | |||
T2434 | LY 303511 | Potassium Channel , TNF , mTOR | |
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K. | |||
T63713 | Mytoxin B | ||
Mytoxin B is a macrocyclic endolipid that acts like LY294002 and is also an ADC cytotoxin (ADC cytotoxin). mytoxin B is able to exploit the PI3K/Akt pathway and thus induce apoptosis. | |||
T37476 | Cyclo(L-Phe-L-Val) | ||
Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It indu... |