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Search Results for " lxrβ "

20

Compounds

Cat No. Product Name Synonyms Targets
T11899 LXRβ agonist-2 Others
LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.
T63989 LXRβ agonist-3
LXRβ agonist-3 is a potent and selective LXRβ (liver X receptor β) agonist (EC50: 0.095 μM). LXRβ agonist-3 effectively inhibits U87EGFRvIII cells (IC50: 3.75 μM). .
T6690 T0901317 Apoptosis , FXR , Liver X Receptor , ROR
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
T15427 GSK2033 Liver X Receptor
GSK2033 is an antagonist of LXR (pIC50s: 7 and 7.4 for LXRα or LXRβ, respectively).
T16930 SR9238 Liver X Receptor
SR9238 is a synthetic agonist of liver X receptor inverse (IC50s: 214 nM and 43 nM for LXRα and LXRβ, respectively).
T63896 BE1218 Liver X Receptor
BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.
TN1055 Licochalcone E TNF , Liver X Receptor , PPAR
Licochalcone E is a potential LXRβ agonist.
T3970 BMS-779788 XL652,EXEL04286652,XL 652,XL-652,BMS-788 Liver X Receptor
BMS-779788 (XL-652) is an LXRα/β partial agonist (IC50: 68/14 nM).
T35973 Cholesterol-5α,6α-epoxide Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176 Others
Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE applicat...
T1783 LXR-623 LXR623,WAY 252623 Liver X Receptor
LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR.
T68316 GAC0003A4 GAC0001E5 Liver X Receptor
GAC0003A4 is a potent LXR inverse agonist with antitumor activity that inhibits the transcription of LXR proteins.GAC0003A4 degrades LXRβ proteins and inhibits the proliferation of PDAC cells in a dose-dependent manner.G...
T7796 TUG-1375 GPR
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2
T27478 GSK3987 Liver X Receptor
GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM.
T25356 E17110 E-17110,E 17110
E17110 is an LXRβ agonist. E17110 exhibited a significant activation effect on LXRβ (EC50: 0.72 μmol/L). E17110 also increased the expression of ABCA1 and ABCG1 in RAW264.7 macrophages. E17110 significantly decreased cel...
T68864 Saringosterol
Saringosterol, also known as Saningosterol and Cystosphaerol, is a selective LXRβ agonist. Saringosterol is racmic at the 24-position.
T14679 XL041 BMS-852927 Liver X Receptor
XL041 (BMS-852927) is an agonist of LXRβ-selective.
T68696 AZ-2
AZ-2 is an inducer of ABCA1 and apoE. It enhances ABCA1 activity and decreases P2X7 receptor activity. AZ-2 activates endogenous LXR signaling but shows no direct LXRα or LXRβ agonist activity.
T75388 FITC-GW3965
FITC-GW3965, a fluorescence-labeled liver X receptor β (LXRβ) agonist, is derived from GW3965 by substituting its trifluoromethyl group with an amide linkage to FITC. This tracer facilitates the study of LXRβ function [1...
T68668 AZ-1
AZ-1 is an inducer of ABCA1 and apoE. It enhances ABCA1 activity and decreases P2X7 receptor activity. AZ-1 activates endogenous LXR signaling but shows no direct LXRα or LXRβ agonist activity.
T6310 GW3965 hydrochloride GW3965 HCl Liver X Receptor
GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).
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TargetMol