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Search Result

Search Results for " loxin "

Targets

Beta Amyloid

15

Compounds

3

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T63540 Astrophloxine Beta Amyloid
Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples from Alzheimer's disease (AD) mice.
T40437L Caloxin 2A1 acetate Proton pump
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate.
T22456 Voreloxin hydrochloride SNS-595 hydrochloride,Vosaroxin Apoptosis , Topoisomerase
Voreloxin hydrochloride (SNS-595 hydrochloride) is a potent inhibitor of Topoisomerase II with broad-spectrum anti-tumor activity.
T16703 Quarfloxin CX-3543 DNA/RNA Synthesis
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...
T16560 Poloxin PLK
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
T25969 Poloxin-2 Poloxin2,Poloxin 2 PLK
Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.
T123923 Altiloxin B
Altiloxin B is a useful organic compound for research related to life sciences. The catalog number is T123923 and the CAS number is 92675-14-4.
T35923 Caloxin 2A1 TFA
Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1].
T40471 Azophloxine Acid red 1,Azophloxine
Azophloxine, also known as acid red 1 (AR1), is a member of synthetic red azo dye family.
T80247 Caloxin 3A1 Calcium Channel
Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps. Specifically, it inhibits plasma membrane calcium pumps (PMCAs) without ...
T37756 Phloxine B
Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positi...
T82789 Caloxin 1B1
Caloxin 1B1, a bioactive peptide, exhibits selective inhibition of PMCA extracellularly by binding preferentially to the extracellular domain 1 of PMCA4 over PMCA1. Identified through a screening process for its high-aff...
T6724 Voreloxin Vosaroxin,AG 7352,SNS-595 Apoptosis , Topoisomerase
Voreloxin (SNS-595) is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.
T40437 Caloxin 2A1
Caloxin 2A1 is an inhibitor peptide of the plasma membrane Ca 2+-ATPase (PMCA) responsible for extracellular signaling. Importantly, Caloxin 2A1 has no impact on the basal Mg 2+-ATPase or Na+-K+-ATPase activities.
T34715 Stemphyloxin I Deacyl-FR 225654
Stemphyloxin I is a phytotoxin from Stemphylium botryosum.
Cat No. Product Name Synonyms Targets
TN4752 Perilloxin COX
Perilloxin possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 microM.
TN3810 Dehydroperilloxin COX
Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.
TN2938 3-Hydroxy-3-acetonyloxindole Others
3-Hydroxy-3-acetonyloxindole is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN2938 and the CAS number is 33417-17-3. 3-Hydroxy-3-acetonyloxindole can be used as a reference standard.

Natural Products

Perilloxin
TN4752
Synonym:
Target: COX
Dehydroperilloxin
TN3810
Synonym:
Target: COX
3-Hydroxy-3-acetonyloxindole
TN2938
Synonym:
Target: Others

Recombinant Proteins

Species：
Human (1)
Mouse (1)
Expression System：
HEK293 Cells (2)
Tag：
His (1)
N-His (1)
Cat No. Product Name Species Expression System
TMPY-02490 LOX-1 Protein, Human, Recombinant (His) Human HEK293 Cells
LOX-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P78380.
TMPK-01168 LOX-1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
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