20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T70132 | HSP-117 dihydrochloride | ||
HSP-117 dihydrochloride is a novel tachykinin NK1-receptor antagonist. | |||
T68769 | HSP-117 free base | ||
HSP-117 free base is a novel tachykinin NK1-receptor antagonist. | |||
T6118 | NVP-HSP990 | HSP990 | Apoptosis , HSP |
NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM). | |||
T3487 | HSP70-IN-1 | Others , HSP | |
HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM). | |||
T34121 | Pramiverine | EMD 9806,HSP 2986,EMD9806,HSP2986,EMD-9806 | |
Pramiverine is a long-acting choline dissolving agent used for gastrointestinal spasms. | |||
TQ0280 | Feretoside | HSP | |
Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1). | |||
T7265 | HSP27 inhibitor J2 | J2 | HSP |
HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function. | |||
T4125 | HSF1A | HSP | |
HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis. | |||
T8189 | Dihydroberberine | Potassium Channel , HSP , HER | |
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti... | |||
T21883 | Gedunin | HSP | |
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation. | |||
T6248 | XL888 | HSP | |
XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis.... | |||
T3652 | KRIBB11 | Apoptosis , HSP | |
KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor. | |||
T8858 | DTHIB | HSP | |
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation. | |||
T6855 | HA15 | Apoptosis , GPR , Others , HSP , Autophagy | |
HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors. | |||
T3527 | TRC051384 | TRC 051384 | HSP |
TRC051384 is a heat shock protein 70 (HSP70) inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke, activates heat shock factor-1 and leads to elevated ... | |||
T5008 | Teprenone | Tetraprenylacetone,Geranylgeranylacetone | HSP |
Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs). | |||
T6558 | KW-2478 | KW2478 | HSP |
KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM. | |||
T7010 | VER-155008 | VER155008 | GPR , HSP , Autophagy |
VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90. | |||
T16994 | Pimitespib | TAS-116 | HSP |
Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively). | |||
T10860 | Col003 | HSP | |
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis. |