15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2354 | UNC 0631 | UNC0631 | Histone Methyltransferase |
UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM). | |||
TQ0232 | UNC0646 | UNC 0646 | Histone Methyltransferase |
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells ... | |||
T17204 | UNC0321 | Histone Methyltransferase | |
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays. | |||
T7697 | BIX-01294 | Histone Methyltransferase , Autophagy | |
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM). | |||
T7194 | CM-272 | Apoptosis , DNA Methyltransferase , Histone Methyltransferase | |
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor. | |||
T1959 | BIX-01294 trihydrochloride | BIX 01294 | Histone Methyltransferase , Autophagy |
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase. | |||
T6820 | D-α-Hydroxyglutaric acid disodium | D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate | ATPase , Others , Reactive Oxygen Species , Endogenous Metabolite , mTOR |
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. | |||
T63351L | MS8511 HCl | MS8511 HCl(2866408-21-9 Free base) | Histone Methyltransferase |
MS8511 HCl is a selective and potent covalent inhibitor of G9a/GLP that acts by targeting cysteine residues in the substrate binding site. MS8511 has anticancer activity and antiproliferative activity and reduces intrace... | |||
T22250 | 5WKS | ZINC97756584 | Others |
5WKS also known as ZINC97756584 is a biochemical. It is a G9a protein inhibitor.G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes H3K9me2, a reversible modification commonly associated with transcrip... | |||
T79776 | ZZM-1220 | Histone Methyltransferase | |
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP. It effectively inhibits H3K9me2 in cells, induces apoptosis in triple-negative breast... | |||
T73517 | RK-701 | ||
RK-701, a highly selective and non-genotoxic G9a inhibitor, exhibits an IC 50 value of 23-27 nM. It selectively up-regulates HbF, γ-Globin, and BGLT3 expression while down-regulating H3K9me2 expression. Additionally, RK-... | |||
T63351 | MS8511 | ||
MS8511, a selective covalent irreversible inhibitor of G9a/GLP, targets a cysteine residue at the substrate binding site, displaying IC50 values of 100 nM (G9a) and 140 nM (GLP), alongside Kd values of 44 nM (G9a) and 46... | |||
T36627 | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | ||
Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used a... | |||
T72244 | CBB1007 trihydrochloride | ||
CBB1007 trihydrochloride is a cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5.27 μM for hLSD1). IC50 Value: 5.27 uM ... | |||
T72388 | CBB1007 hydrochloride | ||
CBB1007 HCl is a cell-permeable amidino-guanidinium compound identified as a potent, reversible, and substrate-competitive inhibitor of LSD1 (IC50 = 5.27 μM for hLSD1). It effectively inhibits LSD1-mediated demethylation... |