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Search Result

Search Results for " gma "

Targets

Sigma receptor

21

Compounds

33

Natural Products

17

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T27420 GMA-839
GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.
T12911 Sigma-1 receptor antagonist 2 Sigma receptor
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
T12912 Sigma-1 receptor antagonist 3 Sigma receptor , HER
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
T12910 Sigma-1 receptor antagonist 1 Sigma receptor
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studie...
T13510 Sigma-LIGAND-1 Sigma receptor
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.
T124527 23-O-Acetylshengmanol 3-O-beta-D-xyloside
23-O-Acetylshengmanol 3-O-beta-D-xyloside is a useful organic compound for research related to life sciences and the catalog number is T124527.
T124674 3β,5α-Dihydroxystigmastan-6-one
3β,5α-Dihydroxystigmastan-6-one is a useful organic compound for research related to life sciences and the catalog number is T124674.
T78734 Sigma-1 receptor antagonist 5 Sigma receptor
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (Ki=4.5 nM (σ1R), 10 nM (σ2R)) and the histamine H3 receptor...
T63048 Sigma-LIGAND-1 hydrochloride
Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand that acts at the DTG (IC50: 16 nM) and PPP (IC50: 19 nM) sites. Sigma-LIGAND-1 hydrochloride is able to act on the dopamine D2 receptor (Ki: 4000 nM).
T125511 Stigmast-7-en-3-ol
Stigmast-7-en-3-ol is a useful organic compound for research related to life sciences and the catalog number is T125511.
T124943 6-Hydroxystigmasta-4,22-dien-3-one
6-Hydroxystigmasta-4,22-dien-3-one is a useful organic compound for research related to life sciences and the catalog number is T124943.
T71495 Monofluoromethylagmatine
Monofluoromethylagmatine is an arginine decarboxylase inhibitor.
T124266 6α-Hydroxystigmast-4-en-3-one
6α-Hydroxystigmast-4-en-3-one is a useful organic compound for research related to life sciences and the catalog number is T124266.
T22077 Eggmanone
Eggmanone (EGM1) is a potent, selective phosphodiesterase 4 (PDE4) antagonist, exhibiting an IC50 of 72 nM specifically for PDE4D3. It shows 40- to 50-fold greater selectivity for PDE4D3 over other phosphodiesterases. Th...
T4808L Agmatine NSC 56332,NSC56332,NSC-56332
Agmatine is decarboxylated arginine.
T33026 Lycophlegmarine
Lycophlegmarine is a bioactive chemical.
T125112 Stigmalactam
Stigmalactam is a useful organic compound for research related to life sciences and the catalog number is T125112.
T79149 Magmas-IN-1 Others
Magmas-IN-1 (compound 9), a small molecule Magmas inhibitor (SMMI), targets the mitochondria-associated granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling molecule and GM-CSF inducible gene in myeloid ce...
T16883 Sigma-2 receptor antagonist 1 Others
Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor.
T74813 Sigma-1 receptor antagonist 4 Sigma receptor
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine's analgesic effects and reverses morphine-induced analgesic tolerance, potentially preventing morphine tolerance...
T84308 (24R)-Stigmastane-3β,5α,6α-triol
Cat No. Product Name Synonyms Targets
T5S1679 Acetylshengmanol Arabinoside Acetylcimigenol 3-O-alpha-L-arabinopyran Others
Acetylcimigenol 3-O-alpha-L-arabinopyranoside is an extract derived from Cimicifuga.
T2967 Stigmasterol Stigmasterin,beta-Stigmasterol MMP , Endogenous Metabolite
Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch...
TN7150 Pygmaniline B 1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea Others
Pygmaniline B (1,3-bis(2,4-dimethoxyphenyl)urea) is a marine derived natural products found in Lichina pygmaea.
T4808 Agmatine sulfate Agmatine sulfate salt Endogenous Metabolite , NO Synthase , Imidazoline Receptor
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy...
T16943 Stigmastanol Endogenous Metabolite
Stigmastanol is a phytosterol.
TN5066 Stigmasta-5,8-dien-3-ol Others
Stigmasta-5,8-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN5066 and the CAS number is 570-72-9.
TN3172 6beta-Hydroxystigmast-4-en-3-one Others
6beta-Hydroxystigmast-4-en-3-one is a natural product for research related to life sciences. The catalog number is TN3172 and the CAS number is 36450-02-9.
TN5062 Stigmast-4-ene-3,6-dione
Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties.
T81086 Stigmast-5-ene-3,7-dione
Stigmast-5-ene-3,7-dione (Compound 10), isolated from the roots, leaves, and twigs of Penianthus longifolius [1], is a naturally occurring chemical entity.
T73201 Stigmane B
Stigmane B, a nuclear factor E2-related factor (Nrf2) activator, exhibits neuroprotective effects by downregulating apoptosis and reactive oxygen species (ROS) generation while increasing antioxidant enzyme activities.
TN5064 Stigmasta-4,22-dien-3-one Others
Stigmasta-4,22-dien-3-one has antioxidant activity.
TN5332 Cucumegastigmane I
Cucumegastigmane I is a natural product of Trichosanthes, Cucurbitaceae. The catalog number is TN5332 and the CAS number is 929881-46-9. Cucumegastigmane I can be used as a reference standard.
TN5068 Stigmastane-3,6-diol Others
Stigmastane-3 beta, 6 alpha-diol and stigmastane-3 beta, 6 beta-diol possess marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, the 50% inhibitory dose is 0.5--1.0...
T16942 Sterigmatocystine Others
Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versico...
TN3254 7alpha-Hydroxystigmasterol Others
7alpha-Hydroxystigmasterol is a natural product of Xanthium, Asteraceae. The catalog number is TN3254 and the CAS number is 64998-19-2. 7alpha-Hydroxystigmasterol can be used as a reference standard.
T83339 3β-(Acetyloxy)stigmast-5-en-7-one
3β-(Acetyloxy)stigmast-5-en-7-one exhibits anti-complement activity [1].
TN6801 Stigmastadienone
Stigmastadienone is a natural product.
TN6201 (1R,6R,9R)-6,9,11-Trihydroxy-4,7-megastigmadien-3-one 11-O-glucoside
(1R,6R,9R)-6,9,11-Trihydroxy-4,7-megastigmadien-3-one 11-O-glucoside is a natural product for research related to life sciences. The catalog number is TN6201 and the CAS number is 289914-68-7.
T83259 6β-Hydroxystigmasta-4,22-dien-3-one
6β-Hydroxystigmasta-4,22-dien-3-one is a steroidal compound that can be isolated from the plant Hedychium coronarium [1].
T83398 23-Acetylshengmanol 3-O-β-D-xylopyranoside Acetylshengmanol xyloside
23-Acetylshengmanol 3-O-β-D-xylopyranoside (Acetylshengmanol xyloside), a 9,19-cyclolanostane type triterpenoid, is isolated from the roots of Actaea pachypoda [1].
TN5285 Stigmast-4-ene-3β,6β-diol
Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
TN5065 Stigmasta-4,25-dien-3-one Others
Stigmasta-4,25-dien-3-one is a natural product for research related to life sciences. The catalog number is TN5065 and the CAS number is 848669-08-9.
TN4763 Phlegmanol C Others
Phlegmanol C is a natural product for research related to life sciences. The catalog number is TN4763 and the CAS number is 1260-05-5.
TN1327 7,22,25-Stigmastatrienol Others
7,22,25-Stigmastatrienol is a natural product
TN5067 Stigmastane-3,5,6-triol Antifection
Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine.
T81608 O-Methylsterigmatocystin
O-Methylsterigmatocystin is a metabolite produced by Aspergillus flavus and Aspergillus parasiticus [1].
T81085 Stigmasta-3,5-dien-7-one
Stigmasta-3,5-dien-7-one is a steroid derivative sourced from Harrisonia abyssinica [1].
TN2908 3,7,16-Trihydroxystigmast-5-ene Others
3,7,16-Trihydroxystigmast-5-ene is a natural product for research related to life sciences. The catalog number is TN2908 and the CAS number is 289056-24-2.
TN5063 Stigmasta-4,22,25-trien-3-one Others
Stigmasta-4,22,25-trien-3-one is a natural product from Callicarpa giraldiana.
TN1337 7Z-Trifostigmanoside I 7-Z-Trifostigmanoside I Others
7-Z-Trifostigmanoside I is a natural product from Polygala hongkongensis Hemsl.
TN2238 Stigmasterol glucoside Others
Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.
TN5294 Stigmasta-4,22-diene-3β,6β-diol
Stigmasta-4,22-diene-3β,6β-diol is a natural product for research related to life sciences. The catalog number is TN5294 and the CAS number is 167958-89-6.
TN5069 (5α)-Stigmastane-3,6-dione Stigmastane-3,6-dione
Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils.

Natural Products

Acetylshengmanol Arabinoside
T5S1679
Synonym: Acetylcimigenol 3-O-alpha-L-arabinopyran
Target: Others
Stigmasterol
T2967
Synonym: Stigmasterin,beta-Stigmasterol
Target: MMP, Endogenous Metabolite
Pygmaniline B
TN7150
Synonym: 1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea
Target: Others
Agmatine sulfate
T4808
Synonym: Agmatine sulfate salt
Target: Endogenous Metabolite, NO Synthase, Imidazoline Receptor
Stigmastanol
T16943
Synonym:
Target: Endogenous Metabolite
Stigmasta-5,8-dien-3-ol
TN5066
Synonym:
Target: Others
6beta-Hydroxystigmast-4-en-3-one
TN3172
Synonym:
Target: Others
Stigmast-4-ene-3,6-dione
TN5062
Synonym:
Target:
Stigmast-5-ene-3,7-dione
T81086
Synonym:
Target:
Stigmane B
T73201
Synonym:
Target:
Stigmasta-4,22-dien-3-one
TN5064
Synonym:
Target: Others
Cucumegastigmane I
TN5332
Synonym:
Target:
Stigmastane-3,6-diol
TN5068
Synonym:
Target: Others
Sterigmatocystine
T16942
Synonym:
Target: Others
7alpha-Hydroxystigmasterol
TN3254
Synonym:
Target: Others
3β-(Acetyloxy)stigmast-5-en-7-one
T83339
Synonym:
Target:
Stigmastadienone
TN6801
Synonym:
Target:
(1R,6R,9R)-6,9,11-Trihydroxy-4,7-megastigmadien-3-one 11-O-glucoside
TN6201
Synonym:
Target:
6β-Hydroxystigmasta-4,22-dien-3-one
T83259
Synonym:
Target:
23-Acetylshengmanol 3-O-β-D-xylopyranoside
T83398
Synonym: Acetylshengmanol xyloside
Target:
Stigmast-4-ene-3β,6β-diol
TN5285
Synonym:
Target:
Stigmasta-4,25-dien-3-one
TN5065
Synonym:
Target: Others
Phlegmanol C
TN4763
Synonym:
Target: Others
7,22,25-Stigmastatrienol
TN1327
Synonym:
Target: Others
Stigmastane-3,5,6-triol
TN5067
Synonym:
Target: Antifection
O-Methylsterigmatocystin
T81608
Synonym:
Target:
Stigmasta-3,5-dien-7-one
T81085
Synonym:
Target:
3,7,16-Trihydroxystigmast-5-ene
TN2908
Synonym:
Target: Others
Stigmasta-4,22,25-trien-3-one
TN5063
Synonym:
Target: Others
7Z-Trifostigmanoside I
TN1337
Synonym: 7-Z-Trifostigmanoside I
Target: Others
Stigmasterol glucoside
TN2238
Synonym:
Target: Others
Stigmasta-4,22-diene-3β,6β-diol
TN5294
Synonym:
Target:
(5α)-Stigmastane-3,6-dione
TN5069
Synonym: Stigmastane-3,6-dione
Target:

Recombinant Proteins

Species：
Human (8)
Mouse (3)
Mycobacterium smegmatis (2)
E. coli (1)
Mycolicibacterium smegmatis (1)
Pongo pygmaeus (1)
Reo-3 (1)
Expression System：
E. coli (8)
HEK293 Cells (8)
P. pastoris (Yeast) (1)
Tag：
C-His-Avi (3)
C-hFc (2)
His (2)
N-6xHis-SUMO (2)
Tag Free (2)
C-His (1)
GST (1)
N-10xHis (1)
N-10xHis, C-Myc (1)
N-6xHis (1)
Cat No. Product Name Species Expression System
TMPY-04662 MAG Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
MAG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is P20917-2.
TMPY-04676 MAG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
MAG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.3 kDa and the accession number is P20917-2.
TMPY-03147 MAG Protein, Human, Recombinant (hFc) Human HEK293 Cells
MAG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.7 kDa and the accession number is P20916-1.
TMPY-02569 MAG Protein, Human, Recombinant (His) Human HEK293 Cells
MAG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P20916.
TMPK-00352 Siglec-4a/MAG Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPK-00278 RGMA Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPK-00279 RGMA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its recept...
TMPH-02996 KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc) Mycolicibacterium smegmatis E. coli
Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,...
TMPH-02997 Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO) Mycobacterium smegmatis E. coli
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPY-01275 14-3-3 sigma Protein, Human, Recombinant Human E. coli
14-3-3 sigma Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28 kDa and the accession number is P31947-1.
TMPH-03404 Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His) Reo-3 E. coli
Stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase...
TMPH-02998 Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His) Mycobacterium smegmatis E. coli
Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is A0QR29.
TMPH-03148 DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) Pongo pygmaeus P. pastoris (Yeast)
DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 31.9 kDa and the accession number is A4H244.
TMPY-02113 14-3-3 sigma Protein, Mouse, Recombinant Mouse E. coli
14-3-3 sigma Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.7 kDa and the accession number is O70456.
TMPY-01263 14-3-3 sigma Protein, Human, Recombinant (GST) Human E. coli
14-3-3 sigma Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 50.1 kDa and the accession number is P31947-1.
TMPH-00576 Agmatinase Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Catalyzes the formation of putrescine from agmatine. Agmatinase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.5 kDa and t...
MAG Protein, Mouse, Recombinant (hFc)
TMPY-04662
Species: Mouse
Expression System: HEK293 Cells
MAG Protein, Mouse, Recombinant (His)
TMPY-04676
Species: Mouse
Expression System: HEK293 Cells
MAG Protein, Human, Recombinant (hFc)
TMPY-03147
Species: Human
Expression System: HEK293 Cells
MAG Protein, Human, Recombinant (His)
TMPY-02569
Species: Human
Expression System: HEK293 Cells
Siglec-4a/MAG Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00352
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His & Avi)
TMPK-00278
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00279
Species: Human
Expression System: HEK293 Cells
KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)
TMPH-02996
Species: Mycolicibacterium smegmatis
Expression System: E. coli
Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)
TMPH-02997
Species: Mycobacterium smegmatis
Expression System: E. coli
14-3-3 sigma Protein, Human, Recombinant
TMPY-01275
Species: Human
Expression System: E. coli
Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His)
TMPH-03404
Species: Reo-3
Expression System: E. coli
Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His)
TMPH-02998
Species: Mycobacterium smegmatis
Expression System: E. coli
DEFB126 Protein, Pongo pygmaeus, Recombinant (GST)
TMPH-03148
Species: Pongo pygmaeus
Expression System: P. pastoris (Yeast)
14-3-3 sigma Protein, Mouse, Recombinant
TMPY-02113
Species: Mouse
Expression System: E. coli
14-3-3 sigma Protein, Human, Recombinant (GST)
TMPY-01263
Species: Human
Expression System: E. coli
Agmatinase Protein, E. coli, Recombinant (His & SUMO)
TMPH-00576
Species: E. coli
Expression System: E. coli
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