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Search Results for " fov "

Targets

37

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7447 Adefovir HBV , Reverse Transcriptase , Telomerase
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.
T19526 Pradefovir mesylate Pradefovir mesilate,Remofovir mesylate,Hepavir B P450
Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM.
T39043 Tenofovir amibufenamide HS-10234 HBV
Tenofovir amibufenamide (HS-10234) (HS-10234) is a Tenofovir prodrug, an antiviral compound with oral activity. Tenofovir amibufenamide inhibits hepatitis B virus (HBV) and can be used in chronic hepatitis B (CHB) studie...
T8736 Cidofovir dihydrate HPMPC,(S)-HPMPC,GS 0504 Others
Cidofovir dihydrate (HPMPC) is an anti-CMV drug, It can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. Cidofovir dihydrate is an ...
TQ0095 Brincidofovir CMX001,HDP-CDV Others , Antiviral , HSV
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.
T41249 Tenofovir alafenamide fumarate GS-7340 fumarate HIV Protease
Tenofovir alafenamide fumarate (GS-7340 fumarate) is an orally available Tenofovir precursor compound Tenofovir alafenamide fumarate has anti-HIV activity and can be used to prevent HIV infection.
T63290 (R,1R)-Tenofovir amibufenamide (R,1R)-HS-10234 Antiviral
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity. Tynofovir is a nucleotide reverse transcriptase inhibitor.
T7111 Tenofovir Disoproxil GS 4331,Bis(POC)-PMPA HBV , HIV Protease , Reverse Transcriptase
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
T28449 Pradefovir ICN-2001-3,MB-6866,ICN-20013,MB-06866,Remofovir HBV
Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converte...
T67816 Alamifovir PM
Alamifovir PM is an analogue of Alamifovir, an HBV-specific antiviral compound.
T1649 Tenofovir PMPA,TDF,GS 1278 HBV , HIV Protease , Reverse Transcriptase
Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIV...
T5832 Besifovir HBV
Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).
T67817 Besifovir PM LB80331 PM HBV
Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B infection.
T7282 Tenofovir alafenamide hemifumarate GS-7340 (hemifumarate),Tenofovir alafenamide fumarate HIV Protease , Reverse Transcriptase
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
T28946 Tenofovir exalidex Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157 Antiviral
Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant HIV strains, including those resistant to multiple nucleosi...
T12814 (S)-Tenofovir (S)-PMPA,(S)-GS 1278,(S)-TDF Others
(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.
T6244 Cidofovir HPMPC,GS 0504,(S)-HPMPC Others , DNA/RNA Synthesis
Cidofovir ((S)-HPMPC) inhibits virus replication by specific inhibition of viral DNA synthesis.
T1675 Adefovir dipivoxil Hepsera,GS 0840,Preveon Others , HBV , Reverse Transcriptase
Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc...
T2409L Tenofovir Disoproxil Fumarate GS-1278 Disoproxil Fumarate,Tenofovir DF HBV , HIV Protease , Reverse Transcriptase
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribe...
T2409 Tenofovir alafenamide GS-7340 HIV Protease , Reverse Transcriptase
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.
T13574 Besifovir Dipivoxil maleate LB80380 maleate Others
Besifovir Dipivoxil (LB80380) maleate is an oral prodrug of LB80317. Besifovir Dipivoxil maleate is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis...
T76921 Befovacimab
Befovacimab (BAY 1093884), a fully human monoclonal IgG2 antibody, binds to the tissue factor pathway inhibitor (TFPI). It is utilized in research for haemophilia A/B [1].
T25023 Alamifovir
Alamifovir is an antiviral drug specific for HBV. It is a purine nucleotide analog prodrug that is active against wild-type and lamivudine-resistant HBV and acts by inhibiting viral DNA initiation and viral DNA packaging...
T40238 Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) displays a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes. Moreover, it demonstrates potent in vitro anti-HIV activity and improves in viv...
T30789 Cefovecin Sodium UK 287,074-02,UK-287,074-02,C13142,D01681,UK287,074-02
Cefovecin Sodium(Convenia) is an antibiotic of the cephalosporin class, licensed for the treatment of skin infections in cats and dogs.
T21775 Tenofovir maleate
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B.
T77147 Relfovetmab
Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .
T24731 Rovafovir Etalafenamide GS9131,GS 9131,GS-9131
Rovafovir Etalafenamide is a prodrug of anti-HIV nucleoside phosphonate.
T71066 Cidofovir sodium
Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in...
T28945 Tenofovir disoproxil aspartate CKD-390,CKD390,CKD 390
Tenofovir disoproxil aspartate, a nucleotide reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection.
T73983 Cidofovir diphosphate tri(triethylamine)
Cidofovir diphosphate triethylamine, an active intracellular metabolite of Cidofovir, acts as a selective inhibitor of viral DNA polymerases. It exhibits inhibitory constants (K_i) of 6.6 μM for human cytomegalovirus (HC...
T1649L Tenofovir hydrate
Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor used in the treatment of HIV and chronic Hepatitis B.
T40239 Tenofovir-C3-O-C15-CF3 ammonium Tenofovir-C3-O-C15-CF3 ammonium
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo.
T37909 Tenofovir diphosphate
Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1]...
T37523 Tenofovir diphosphate (sodium salt)
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA...
T37910 Tenofovir diphosphate triethylamine
Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1].
T71036 Adefovir monophosphate
Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic...

Compounds

Adefovir
T7447
Synonym:
Target: HBV, Reverse Transcriptase, Telomerase
Pradefovir mesylate
T19526
Synonym: Pradefovir mesilate,Remofovir mesylate,Hepavir B
Target: P450
Tenofovir amibufenamide
T39043
Synonym: HS-10234
Target: HBV
Cidofovir dihydrate
T8736
Synonym: HPMPC,(S)-HPMPC,GS 0504
Target: Others
Brincidofovir
TQ0095
Synonym: CMX001,HDP-CDV
Target: Others, Antiviral, HSV
Tenofovir alafenamide fumarate
T41249
Synonym: GS-7340 fumarate
Target: HIV Protease
(R,1R)-Tenofovir amibufenamide
T63290
Synonym: (R,1R)-HS-10234
Target: Antiviral
Tenofovir Disoproxil
T7111
Synonym: GS 4331,Bis(POC)-PMPA
Target: HBV, HIV Protease, Reverse Transcriptase
Pradefovir
T28449
Synonym: ICN-2001-3,MB-6866,ICN-20013,MB-06866,Remofovir
Target: HBV
Alamifovir PM
T67816
Synonym:
Target:
Tenofovir
T1649
Synonym: PMPA,TDF,GS 1278
Target: HBV, HIV Protease, Reverse Transcriptase
Besifovir
T5832
Synonym:
Target: HBV
Besifovir PM
T67817
Synonym: LB80331 PM
Target: HBV
Tenofovir alafenamide hemifumarate
T7282
Synonym: GS-7340 (hemifumarate),Tenofovir alafenamide fumarate
Target: HIV Protease, Reverse Transcriptase
Tenofovir exalidex
T28946
Synonym: Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157
Target: Antiviral
(S)-Tenofovir
T12814
Synonym: (S)-PMPA,(S)-GS 1278,(S)-TDF
Target: Others
Cidofovir
T6244
Synonym: HPMPC,GS 0504,(S)-HPMPC
Target: Others, DNA/RNA Synthesis
Adefovir dipivoxil
T1675
Synonym: Hepsera,GS 0840,Preveon
Target: Others, HBV, Reverse Transcriptase
Tenofovir Disoproxil Fumarate
T2409L
Synonym: GS-1278 Disoproxil Fumarate,Tenofovir DF
Target: HBV, HIV Protease, Reverse Transcriptase
Tenofovir alafenamide
T2409
Synonym: GS-7340
Target: HIV Protease, Reverse Transcriptase
Besifovir Dipivoxil maleate
T13574
Synonym: LB80380 maleate
Target: Others
Befovacimab
T76921
Synonym:
Target:
Alamifovir
T25023
Synonym:
Target:
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
T40238
Synonym: Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Target:
Cefovecin Sodium
T30789
Synonym: UK 287,074-02,UK-287,074-02,C13142,D01681,UK287,074-02
Target:
Tenofovir maleate
T21775
Synonym:
Target:
Relfovetmab
T77147
Synonym:
Target:
Rovafovir Etalafenamide
T24731
Synonym: GS9131,GS 9131,GS-9131
Target:
Cidofovir sodium
T71066
Synonym:
Target:
Tenofovir disoproxil aspartate
T28945
Synonym: CKD-390,CKD390,CKD 390
Target:
Cidofovir diphosphate tri(triethylamine)
T73983
Synonym:
Target:
Tenofovir hydrate
T1649L
Synonym:
Target:
Tenofovir-C3-O-C15-CF3 ammonium
T40239
Synonym: Tenofovir-C3-O-C15-CF3 ammonium
Target:
Tenofovir diphosphate
T37909
Synonym:
Target:
Tenofovir diphosphate (sodium salt)
T37523
Synonym:
Target:
Tenofovir diphosphate triethylamine
T37910
Synonym:
Target:
Adefovir monophosphate
T71036
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00519 Gastrokine 1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in...
TargetMol