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(R,1R)-Tenofovir amibufenamide

🥰Excellent
Catalog No. T63290Cas No. 1571076-37-3
Alias (R,1R)-HS-10234

(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) is an orally administered Tenofovir prodrug with antiviral activity. Tenofovir is a nucleotide reverse transcriptase inhibitor.

(R,1R)-Tenofovir amibufenamide
Other Forms of (R,1R)-Tenofovir amibufenamide:
Tenofovir amibufenamideT390431571076-26-0
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(R,1R)-Tenofovir amibufenamide

🥰Excellent
Purity: 98.95%
Catalog No. T63290Alias (R,1R)-HS-10234Cas No. 1571076-37-3
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) is an orally administered Tenofovir prodrug with antiviral activity. Tenofovir is a nucleotide reverse transcriptase inhibitor.
Pack SizePriceAvailabilityQuantity
1 mg$53In Stock
5 mg$135In Stock
10 mg$200In Stock
25 mg$345In Stock
50 mg$466In Stock
100 mg$630In Stock
200 mg$833In Stock
1 mL x 10 mM (in DMSO)$148In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.95%
ee:99.36%
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COA LCMS HNMR ORP CSFC PNMR

Product Introduction

Bioactivity
Description
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) is an orally administered Tenofovir prodrug with antiviral activity. Tenofovir is a nucleotide reverse transcriptase inhibitor.
Synonyms(R,1R)-HS-10234
Chemical Properties
Molecular Weight490.49
FormulaC22H31N6O5P
Cas No.1571076-37-3
SmilesC([C@H](OCP(OC1=CC=CC=C1)(NC(C(OC(C)C)=O)(C)C)=O)C)N2C=3C(N=C2)=C(N)N=CN3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 9 mg/mL (18.35 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0388 mL10.1939 mL20.3878 mL101.9389 mL
5 mM0.4078 mL2.0388 mL4.0776 mL20.3878 mL
10 mM0.2039 mL1.0194 mL2.0388 mL10.1939 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tenofovir amibufenamideHS-10234HS10234HS 10234Antiviral
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