faah — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T67745	CB2R/FAAH modulator-2		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an...		Cannabinoid Receptor , FAAH
T11256	FAAH inhibitor 1	Benzothiazole analog 3	FAAH
	FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.		FAAH
T67896	CB2R/FAAH modulator-1		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and i...		Cannabinoid Receptor , FAAH
T15268	FAAH-IN-2	O-Desmorpholinopropyl Gefitinib	FAAH , Autophagy
	FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).		FAAH , Autophagy
T67747	CB2R/FAAH modulator-3		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ...		Cannabinoid Receptor , FAAH
T63536	Dual FAAH/sEH-IN-1		FAAH , Epoxide Hydrolase
	Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.		FAAH , Epoxide Hydrolase
T6714	URB-597	KDS-4103,FAAH Inhibitor II	Mitophagy , FAAH , Autophagy
	URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.		Mitophagy , FAAH , Autophagy
T11255	FAAH-IN-1		FAAH
	FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.		FAAH
T82421	FAAH/cPLA2α-IN-1		Phospholipase
	FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (IC50s) of 32 nM for FAAH and 47 nM for cPLA2α [1].		Phospholipase
T62558	FAAH-IN-5
	FAAH-IN-5 (Compound 7) is a relatively selective, irreversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50: 10.5 nM). FAAH-IN-5 has low PAMPA (parallel artificial membrane permeability assay) permeability.
T73302	FAAH-IN-7
	FAAH-IN-7, a potent and reversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrates significant neuroprotective effects, particularly by mitigating oxidative stress in 1321N1 astrocytes. With an IC50 value of...
T62671	FAAH/MAGL-IN-3
	FAAH/MAGL-IN-3 (Compound 10) is an irreversible dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) that acts on FAAH (IC50: 179 nM) and MAGL (IC50: 759 nM). FAAH/MAGL-IN-3 showed littl...
T61198	FAAH/MAGL-IN-1
	FAAH/MAGL-IN-1, also known as compound SIH 3, is a highly effective inhibitor of FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). It exhibits IC50 values of 31 nM and 29 nM against FAAH and MAGL, res...
T26311	URB532	URB-532,FAAH Inhibitor I,FAAH Inhibitor-I,URB 532
	URB532 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor.
T61707	FAAH/MAGL-IN-2
	FAAH/MAGL-IN-2, a potent and reversible inhibitor of FAAH and MAGL, demonstrates oral activity and the ability to cross the blood-brain barrier. It exhibits IC50 values of 11 nM for FAAH and 36 nM for MAGL (Ki values of ...
T8927	WWL 154	WWL-154	FAAH
	WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor.		FAAH
T28353	PDP-EA		FAAH
	PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.		FAAH
T9967	MAGL-IN-5		Lipid
	MAGL-IN-5 is a non-selective lipase inhibitor.		Lipid
T3215	JNJ-42165279	JNJ42165279	FAAH , Autophagy
	JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 re...		FAAH , Autophagy
T8646	URB937		FAAH
	URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM).		FAAH