ebola — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3S1852	Cephaeline hydrochloride		Others , Virus Protease , Influenza Virus
	Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.		Others , Virus Protease , Influenza Virus
TN1480	Cephaeline		Virus Protease , Influenza Virus , HIF
	Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.		Virus Protease , Influenza Virus , HIF
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease
	FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective ...
TP2184	Matrix protein (3-15) [Zaire ebolavirus]		Others
	matrix protein (3-15) [Zaire ebolavirus] is a peptide of the structural proteins linking the viral envelope with the zaire ebolavirus core. Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavi...		Others
T8502	N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide		Influenza Virus
	N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibited the Ebola virus with EC50 of 3.9 μM.		Influenza Virus
T8686	VUN65671		Others
	Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses.		Others
T17190	U18666A		Others , HCV Protease
	U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.		Others , HCV Protease
T16697	Pyronaridine tetraphosphate		Topoisomerase
	Pyronaridine tetraphosphate is an orally active, mannitol-containing inhibitor of DNA topoisomerase 2 and erythrocyte cytokine with antimalarial and antitumour activity.Pyronaridine tetraphosphate treats P. falciparum an...		Topoisomerase
T7766	Remdesivir	GS-5734	SARS-CoV , DNA/RNA Synthesis
	Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viru...		SARS-CoV , DNA/RNA Synthesis
T80640	EBOV-IN-1		Influenza Virus
	EBOV-IN-1 is an adamantane dipeptide piperazine inhibitor against Ebola virus (EBOV) that inhibits EBOV infection and suppresses pseudotypic EBOV infection.		Influenza Virus
T8501	3-Phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-tricyclo[3.3.1.13,7]decane-1-carboxamide		Influenza Virus
	3- Phenyl- N- [1- (phenylmethyl) - 4- piperidinyl] -tricyclo[3.3.1.13, 7] decane- 1- carboxamide with antiviral activity against Ebola virus that targets the surface-exposed glycoprotein and inhibits viral entry into hos...		Influenza Virus
T68749	EBOV-IN-C31
	EBOV-IN-C31 is a novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties.
T77105	Odesivimab
	Odesivimab, a humanized monoclonal antibody, targets the Ebola virus glycoprotein, exhibiting a binding affinity (K D value) of 7.74 nM for the recombinant histidine-tagged ectodomain of the Makona strain Ebola virus gly...
T62709	EBOV-GP-IN-1
	EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).
T82996	Antiviral agent 27
	Antiviral agent 27 (Compound 12) exhibits significant activity against the Ebola virus, with an EC50 value of 14 nM [1].
T77051	Larcaviximab
	Larcaviximab (c4G7-N) is a chimeric monoclonal antibody of the IgG1 kappa class, specifically targeting the Ebola virus glycoprotein [1].
T60623	As-358
	As-358 has inhibitory effects against Ebola virus (IC50 = 47.5 μM) and Marburg virus (IC50 = 3.7 μM) [1].
T77119	Porgaviximab
	Porgaviximab is a monoclonal antibody that can be used Ebola infection research [1] .
T39335	Anti-virus agent 1	Anti-virus agent 1,Remdesivir isopropyl ester analog
	Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy. It is primarily utilized in the study of coronavirus and Ebola virus (EBOV).
T71618	Oxocarbazate
	Oxocarbazate, also known as CID23631927, is an inhibitor of human cathepsin L. In the cathepsin L inhibition assay, The oxocarbazate caused a time-dependent 17-fold drop in IC50 from 6.9 nM (no preincubation) to 0.4 nM ...