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Remdesivir

Catalog No. T7766 CAS 1809249-37-3

Synonyms: GS-5734

Purity 99.95% Datasheet

Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)

Remdesivir, CAS 1809249-37-3

Pack Size	Availability	Price/USD
1 mg	In stock	189.00
5 mg	In stock	474.00
10 mg	In stock	703.00
1 mL * 10 mM (in DMSO)	In stock	713.00

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Purity 97.62%

HNMR HPLC COA Datasheet

Purity 99.90%

HNMR HPLC COA Datasheet

Purity 99.93%

HNMR HPLC COA Datasheet

Purity 98.00%

HNMR COA Datasheet

Purity 99.95%

HNMR HPLC COA Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)
Targets&IC50	SARS-CoV :ic50 74 nM (EC50), MERS-CoV :ic50 74 nM (EC50), MHV,

Synonyms	GS-5734
Purity	99.95%
Appearance	solid
Molecular Weight	602.58
Formula	C27H35N6O8P
CAS No.	1809249-37-3

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 125 mg/mL (207.44 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Andrea J Pruijssers , et al. Nucleoside analogues for the treatment of coronavirus infections[J]. Curr Opin Virol. 2019 Apr;35:57-62. 1. Agostini M L , Andres E L , Sims A C , et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease[J]. Mbio, 2018, 9(2):e00221-18. 2. Momattin H , et al. A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)[J]. Travel Med Infect Dis. 2019 Jul - Aug;30:9-18. 2. Wang M , Cao R , Zhang L , et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro[J]. cell research.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.