14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11231 | ERRγ Inverse Agonist 1 | Estrogen/progestogen Receptor | |
ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1]. | |||
T60772 | ERRγ agonist-1 | ||
ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1]. | |||
T74840 | ERRγ agonist-2 | ||
ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a K d value of 6.5 μM. ERRγ agonist-2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ agonist-2 has antimicrobial, anti-coa... | |||
T2250 | DY131 | DY 131,GSK 9089,DY-131 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Smo |
DY131 (DY-131) is a novel selective agonist of ERRβ and ERRγ. | |||
T15191 | PROTAC ERRα ligand 1 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively). | |||
T2177 | Kaempferol | Kempferol,Robigenin | Apoptosis , Estrogen Receptor/ERR , Mitophagy , Estrogen/progestogen Receptor , HIV Protease , Endogenous Metabolite , Parasite , Autophagy |
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities. | |||
T8370 | GSK5182 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species | |
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM) | |||
T7709 | (E/Z)-GSK5182 | GSK5182(Z/E) | Estrogen/progestogen Receptor , ROS |
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating ... | |||
T7904 | SR 19881 | Estrogen/progestogen Receptor | |
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay). | |||
T77552 | SLU-PP-1072 | Apoptosis , Estrogen/progestogen Receptor | |
SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.SLU-PP-1072 is used to study prostate cancer (PCa). | |||
T77577 | SLU-PP-332 | Estrogen/progestogen Receptor | |
SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula... | |||
T11230 | ERRα antagonist-1 | ERR+/- antagonist-1,ERRa antagonist-1 | Estrogen/progestogen Receptor |
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coac... | |||
T73152 | SLU-PP-915 | ||
SLU-PP-915 is an agonist for Estrogen Related Receptors (ERR), exhibiting an EC50 value of roughly 400 nM across ERRα, ERRβ, and ERRγ. This compound shows promise for applications in enhancing oxidative metabolism and ma... | |||
T39837 | PROTAC ERRα Degrader-3 | ||
PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein. At a concentration of 30 nM, this compound exhibits a remarkable degradation capabilit... |