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Search Results for " errγ "

14

Compounds

Cat No. Product Name Synonyms Targets
T11231 ERRγ Inverse Agonist 1 Estrogen/progestogen Receptor
ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist (IC 50=40 nM) [1].
T60772 ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1].
T74840 ERRγ agonist-2
ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a K d value of 6.5 μM. ERRγ agonist-2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ agonist-2 has antimicrobial, anti-coa...
T2250 DY131 DY 131,GSK 9089,DY-131 Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Smo
DY131 (DY-131) is a novel selective agonist of ERRβ and ERRγ.
T15191 PROTAC ERRα ligand 1 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).
T2177 Kaempferol Kempferol,Robigenin Apoptosis , Estrogen Receptor/ERR , Mitophagy , Estrogen/progestogen Receptor , HIV Protease , Endogenous Metabolite , Parasite , Autophagy
Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.
T8370 GSK5182 Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Reactive Oxygen Species
GSK5182 is a highly selective inverse estrogen-related receptor γ agonist (IC50 : 79 nM)
T7709 (E/Z)-GSK5182 GSK5182(Z/E) Estrogen/progestogen Receptor , ROS
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating ...
T7904 SR 19881 Estrogen/progestogen Receptor
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).
T77552 SLU-PP-1072 Apoptosis , Estrogen/progestogen Receptor
SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.SLU-PP-1072 is used to study prostate cancer (PCa).
T77577 SLU-PP-332 Estrogen/progestogen Receptor
SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula...
T11230 ERRα antagonist-1 ERR+/- antagonist-1,ERRa antagonist-1 Estrogen/progestogen Receptor
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coac...
T73152 SLU-PP-915
SLU-PP-915 is an agonist for Estrogen Related Receptors (ERR), exhibiting an EC50 value of roughly 400 nM across ERRα, ERRβ, and ERRγ. This compound shows promise for applications in enhancing oxidative metabolism and ma...
T39837 PROTAC ERRα Degrader-3
PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein. At a concentration of 30 nM, this compound exhibits a remarkable degradation capabilit...
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