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Search Results for " drp1 "

12

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T62687 Drp1-IN-1
Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).
T73456 DRP1i27
DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and ...
TP1947L P110 TFA Others
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.
T1907 Mdivi-1 Mitochondrial division inhibitor 1 Apoptosis , Mitophagy , Dynamin , Autophagy
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondrial autophagy.
T1848 Dynasore Dynamin Inhibitor I Dynamin , Virus Protease , Autophagy , HSV
Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, ...
T37023 MB 0223
Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fu...
T68788 Ellipticine quinone
Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency tha...
T27537 Hexafluoro
Hexafluoro is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrates activity in Vemurafenib-resistant melanoma in vivo.
T27551 Honokiol DCA Honokiol Bis-Dichloroacetate
Honokiol DCA is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo...
TP1947 P110
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen...
T83057 Anti-inflammatory agent 49
Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrial dysfunction. It exhibits an in vitro IC50 value of 270 nM for inhi...
T36490 AZT triphosphate TEA
AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT tr...
Cat No. Product Name Synonyms Targets
T3898 Schaftoside APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside Dynamin , Antioxidant , TLR , MyD88 , Mitochondrial Metabolism , Autophagy
Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01210 DENR Protein, Human, Recombinant (His & SUMO) Human E. coli
DENR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.0 kDa and the accession number is O43583.
TMPH-01255 DNM1L Protein, Human, Recombinant (His & Myc) Human E. coli
DNM1L Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 84.4 kDa and the accession number is O00429.
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