dat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23965	DAT 582	DAT582,DAT-582
	DAT 582 is a novel serotonin3 receptor antagonist. It is also an effective and long-lasting antiemetic agent
T70527	DAT-230
	DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230 -tr...
T25290	DAT1	DAT-1,DAT 1
	DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.
T5165	10-Deacetyltaxol	10-DAT,10-Desacetyl Paclitaxel,Deacetyltaxol,10-deacetyl-paclitaxel,Deacetyl Paclitaxel	Others , Microtubule Associated
	10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.		Others , Microtubule Associated
TN6552	5,7-Dimethoxyluteolin		Dopamine Receptor
	5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.		Dopamine Receptor
T0322	Fipexide		Dopamine Receptor , AChR
	Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...		Dopamine Receptor , AChR
T22714	Decynium 22		Others
	Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor		Others
T6414	Bisacodyl	Fenilaxan,Dulcolax,Brocalax	Others
	Bisacodyl (Fenilaxan) is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation.		Others
T70525	ARC39
	ARC39 is acid sphingomyelinase inhibitor (IC50 =20 nM).
T1871	GBR 12935 dihydrochloride	GBR12935,GBR-12935,GBR 12935	Dopamine Receptor
	GBR 12935 dihydrochloride (GBR 12935) can induce the increase of the extracellular levels of dopamine to basal levels.		Dopamine Receptor
T1993	J-147	J147	Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
	J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T39429	AHN 1-055 hydrochloride	3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride	Dopamine Receptor
	AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).		Dopamine Receptor
T11087	DOV-216,303 Free Base	DOV-216303	Dopamine Receptor , Serotonin Transporter , Norepinephrine
	DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.		Dopamine Receptor , Serotonin Transporter , Norepinephrine
T3526	Dasotraline hydrochloride	SEP-225289 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe...
T10758L	Centanafadine hydrochloride	EB-1020 hydrochloride	Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
	Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T7745	Diclofensine hydrochloride	Ro 8-4650 hydrochloride	Others , Dopamine Receptor
	Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function		Others , Dopamine Receptor
T2092	Amitifadine hydrochloride	DOV-21947 hydrochloride,EB-1010 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T69807	EGFR-IN-451
	EGFR-IN-451 is an EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis.
T7153	Vanoxerine dihydrochloride	GBR-12909 dihydrochloride,I893 dihydrochloride	Dopamine Receptor
	Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)		Dopamine Receptor
T0991	Desipramine hydrochloride	NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
	Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...