d1-receptors — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2226	Pergolide mesylate	Pergolide mesylate salt,LY127809,Pergolide methanesulfonate	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T4117	Zuclopenthixol	cis-Clopenthixol,Cisordinol,(Z)-Clopenthixol	Dopamine Receptor
	Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.		Dopamine Receptor
T67729	UCM-1306		Dopamine Receptor
	UCM-1306 is a potent and orally active allosteric modulator (PAM) of human dopamine D1 receptor. UCM-1306 could increase the maximal effect of endogenous dopamine (DA) both in human and mouse D1 receptors. UCM-1306 could...		Dopamine Receptor
T0074L	Chlorprothixene hydrochloride	NSC 78193,Minithixen,Truxal hydrochloride,NSC 56379,NSC 169899,Minithixen hydrochloride	Dopamine Receptor , 5-HT Receptor , Antibacterial , AChR , Histamine Receptor
	Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical an...
T60835	SKF83959		Dopamine Receptor
	SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent ...		Dopamine Receptor
T22921	LE 300		Dopamine Receptor , 5-HT Receptor
	dopamine D1 receptor antagonist		Dopamine Receptor , 5-HT Receptor
T21446	Rotigotine Hydrochloride	Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp...		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T14767	BP 897 hydrochloride		Dopamine Receptor
	BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ...		Dopamine Receptor
T23265	RS 67333 hydrochloride	RS 67333 (hydrochloride),RS 67333 HCl	5-HT Receptor
	RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu...		5-HT Receptor
T28167	NGB 2904	NGB2904 HCl,NGB-2904,NGB2904	Others , Dopamine Receptor , 5-HT Receptor
	NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag...		Others , Dopamine Receptor , 5-HT Receptor
T9100	BP 897	2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-	Dopamine Receptor
	BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ...		Dopamine Receptor
T0162	Quetiapine	ICI204636,Quetiapin	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
	Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T2592	Ropinirole hydrochloride	SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl	Dopamine Receptor
	Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti...		Dopamine Receptor
T2546	Pimozide	R6238	Potassium Channel , Dopamine Receptor , Adrenergic Receptor , STAT
	Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby...
T4117L2	Zuclopenthixol dihydrochloride
	Zuclopenthixol dihydrochloride is an D1 and D2 dopamine receptors antagonist.
T30603	BT-Sch
	Bt-sch is an imaging agent based on D1 and D2 receptors of dopamine.
T29213	Zelandopam free base	YM-435,YM435,MYD-37,MYD37,Zelandopam
	Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodil...
TQ0315	Tandospirone	SM-3997	5-HT Receptor
	Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis: 1300-41000 nM).		5-HT Receptor
T68193	Clopenthixol
	Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
T69103	Clopenthixol decanoate
	Clopenthixol decanoate is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.