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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9831 | MKC-1 | Ro-31-7453 | Apoptosis , Akt , Microtubule Associated , mTOR |
MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format... | |||
T16961 | Supinoxin | RX-5902 | Apoptosis , DNA/RNA Synthesis |
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50... | |||
T6866 | AUZ 454 | K03861 | CDK |
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. | |||
T11421 | Glutaminase-IN-1 | CB839 derivative | transporter |
Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model. | |||
T36439 | Gramicidin A | Antibacterial , HIF , Parasite | |
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t... | |||
T10106 | 3-arylisoquinolinamine derivative | Others | |
3-arylisoquinolinamine derivative is a compound with antitumor activity. |