Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 43.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. |
Targets&IC50 | CDK2 (WT):50 nM(Kd), CDK2 (C118L):18.6 nM(Kd), CDK2 (C118L/A144C):9.7 nM(Kd), CDK2 (A144C):15.4 nM(Kd) |
In vitro | K03861 inhibits CDK2 activity by competing with binding of activating cyclins. [1] |
Synonyms | K03861 |
Molecular Weight | 501.5 |
Formula | C24H26F3N7O2 |
CAS No. | 853299-07-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 12 mg/mL (23.9 mM)
DMSO: 93 mg/mL (185.4 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AUZ 454 853299-07-7 Cell Cycle/Checkpoint CDK ACHN AUZ454 Caki-1 cells K 03861 Cyclin dependent kinase Inhibitor inhibit CDK2 K03861 K-03861 AUZ-454 inhibitor