cyp2b6 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T37784	2,6-Dimethylquinoline		P450
	2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.		P450
T7788	2-Phenyl-2-(1-piperidinyl)propane		Others
	2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine		Others
T21425	Mephenytoin	Mesantoin,Methoin,Insulton,Phenantoin,Methylphenetoin	P450
	Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.		P450
T12146	N-Desmethyl-Apalutamide	N-Desmethyl Apalutamide	P450 , Androgen Receptor
	N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.		P450 , Androgen Receptor
T0182L	Clopidogrel hydrogen sulfate	(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel	P450 , P2Y Receptor
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.		P450 , P2Y Receptor
T5594	Cedrol		P450 , Antifungal
	Cedrol is a cedrane sesquiterpenoid and a tertiary alcohol,Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respectively)		P450 , Antifungal
T11218	ε-Viniferin	epsilon-Viniferin	P450
	ε-Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.		P450
TN1702	Glycycoumarin		P450 , JNK , AMPK , Autophagy
	Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.		P450 , JNK , AMPK , Autophagy
T3818	Fraxinol		Others , P450
	Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an...		Others , P450
T1443	Memantine hydrochloride	Namenda,Memantine HCl,D-145 (hydrochloride)	P450 , GluR , NMDAR , Autophagy , iGluR
	Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.		P450 , GluR , NMDAR , Autophagy , iGluR
T1149	Fenofibrate	Procetofen,Lipanthyl,Lipantil	P450 , PPAR , Autophagy
	Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.		P450 , PPAR , Autophagy
T8079	α-Terpinyl acetate	Terpinyl Acetate	Others , P450
	α-Terpinyl acetate is a natural compound found in several essential oils, is a flavouring agent.		Others , P450
T37162	8-hydroxy Efavirenz
	8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B...
T24135	HEC72702	HEC-72702,HEC 72702
	HEC72702 is a novel Hepatitis B virus capsid inhibitor, based on clinical candidate GLS4. HEC72702 was found to display no induction of the CYP1A2, CYP3A4, or CYP2B6 enzyme at the high concentration of 10 μM.