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2,6-Dimethylquinoline

2,6-Dimethylquinoline
2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.
Catalog No. T37784Cas No. 877-43-0
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Purity:99.92%
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2,6-Dimethylquinoline

Purity: 99.92%
Catalog No. T37784Cas No. 877-43-0

2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.
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Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Product Introduction

Bioactivity
Description
2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.
Targets&IC50
CYP2B6:480 μM, CYP1A2:3.3 μM
Chemical Properties
Molecular Weight157.21
FormulaC11H11N
Cas No.877-43-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (318.05 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.3609 mL31.8046 mL63.6092 mL318.0459 mL
5 mM1.2722 mL6.3609 mL12.7218 mL63.6092 mL
10 mM0.6361 mL3.1805 mL6.3609 mL31.8046 mL
20 mM0.3180 mL1.5902 mL3.1805 mL15.9023 mL
50 mM0.1272 mL0.6361 mL1.2722 mL6.3609 mL
100 mM0.0636 mL0.3180 mL0.6361 mL3.1805 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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