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2,6-Dimethylquinoline

Name: 2,6-Dimethylquinoline
Brand: TargetMol
SKU: T37784
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T37784Cas No. 877-43-0

2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.

2,6-Dimethylquinoline

🥰Excellent

Purity: 99.89%

Catalog No. T37784Cas No. 877-43-0

Pack Size	Price	Availability
200 mg	$30	In Stock
500 mg	$41	In Stock
1 g	$56	In Stock
2 g	$80	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 µM, respectively.
Targets&IC50	CYP1A2:3.3 μM, CYP2B6:480 μM

Chemical Properties

Molecular Weight	157.21
Formula	C₁₁H₁₁N
Cas No.	877-43-0
Smiles	Cc1ccc2nc(C)ccc2c1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (318.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.3609 mL	31.8046 mL	63.6092 mL	318.0459 mL
5 mM	1.2722 mL	6.3609 mL	12.7218 mL	63.6092 mL
10 mM	0.6361 mL	3.1805 mL	6.3609 mL	31.8046 mL
20 mM	0.3180 mL	1.5902 mL	3.1805 mL	15.9023 mL
50 mM	0.1272 mL	0.6361 mL	1.2722 mL	6.3609 mL
100 mM	0.0636 mL	0.3180 mL	0.6361 mL	3.1805 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc