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20

Compounds

Cat No. Product Name Synonyms Targets
T22009 CB2 receptor agonist 2 ZINC72105556,4-Quinolone-3-Carboxamide Furan CB2 Agonist Cannabinoid Receptor
CB2 receptor agonist 2 (ZINC72105556) is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.
T10696 CB2 modulator 1 Cannabinoid Receptor
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
T24097 CB2 receptor agonist 3 GP-2A,GP 2A,GP2A
GP 2A is a selective agonist of CB2 receptor.
T82771 CB2-H
CB2-H is a dual-channel fluorescent probe designed for the concurrent detection of HOCl and ONOO- with two separate channels that avoid spectral cross-interference. It facilitates dual-channel fluorescence imaging to mon...
T62631 CB2 receptor antagonist 1
Hexyl resorcinol derivative 29 is a CB2 selective competitive antagonist/reverse agonist demonstrating notable potency. Meanwhile, Olivanol and 5-(2-methyloctane-2-yl) resorcinol derivatives 23 and 24 exhibit substantial...
T82772 CB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM. It engages in strong interactions with residues L17, W6.48, V6.51, and C7.42 [1].
T79577 CB2 PET Radioligand 1 Cannabinoid Receptor
CB2 PET Radioligand 1 (compound [18F]9) is a positron emission tomography (PET) radioligand with high affinity for the human cannabinoid receptor 2 (hCB2, Ki=7.7 nM). It is synthesized via Cu-mediated 18F-fluorination an...
TN2268 Tetrahydromagnolol Cannabinoid Receptor , GPR , GABA Receptor
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
T9687 MAGL-IN-4 His121 ARG57 Lipase
MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
T12306 OMDM-5 Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM).
T12302 OMDM-1 (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide Endogenous Metabolite
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM.
T37075 CB2R PAM Ec2la Cannabinoid Receptor
CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive mutational modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTPγS binding to CB2 receptors, but has no effect in the abs...
T67896 CB2R/FAAH modulator-1 Cannabinoid Receptor , FAAH
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and i...
T67747 CB2R/FAAH modulator-3 Cannabinoid Receptor , FAAH
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ...
T25209 CB29 CB-29,CB 29 Dehydrogenase
CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
T8839 ICCB280 Apoptosis , Others
ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavo...
T67745 CB2R/FAAH modulator-2 Cannabinoid Receptor , FAAH
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an...
T10697 CB2R-IN-1 Others
CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).
T82770 CB2R agonist 2 Cannabinoid Receptor
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].
T82769 CB2R agonist 3 Cannabinoid Receptor
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [1].
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