c-59 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2242	Wnt-C59	C59	Wnt/beta-catenin , Porcupine
	Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.		Wnt/beta-catenin , Porcupine
T72322	R 59-022 hydrochloride	DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride	5-HT Receptor , PKC
	R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R...		5-HT Receptor , PKC
T2116	AEE788	NVP-AEE 788	Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl
	AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.		Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl
T16709	R 59-022	Diacylglycerol kinase inhibitor I,DKGI-I	Others
	R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits ...		Others
T76522	HCV Core Protein (59-68)
	HCV Core Protein (59-68) is a peptide comprising residues 59-68 from the core protein of the Hepatitis C virus (HCV) [1].
T123989	Solanapyrone C
	Solanapyrone C is a useful organic compound for research related to life sciences. The catalog number is T123989 and the CAS number is 88899-59-6.
T70424	EBI-907
	EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also...
T35987	CAY10563	CAY10563
	S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m...
T35988	CAY10564
	S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m...
T38021	Obafluorin
	Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.1 It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all). \|1. Pu, Y., Lowe, C., Sailer, M., et al....
T21295	BIX02189	BIX 02189	ERK , MEK
	BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).		ERK , MEK
T9470	HPK1-IN-7		MAPK
	HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).		MAPK
T35712	Debutyldronedarone hydrochloride	SR35021 hydrochloride
	N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbut...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv...