bip — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14613	BIP-135		GSK-3
	BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor. With IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect[1].		GSK-3
T30480	BiP inducer X	BIX	Apoptosis
	BiP inducer X (BIX) is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.		Apoptosis
T65842	Fmoc-Bip(4,4')-OH
	Fmoc-Bip(4,4')-OH is a useful organic compound for research related to life sciences. The catalog number is T65842 and the CAS number is 199110-64-0.
T65855	Fmoc-D-Bip(4,4’)-OH
	Fmoc-D-Bip(4,4’)-OH is a useful organic compound for research related to life sciences. The catalog number is T65855 and the CAS number is 205526-38-1.
T10463	Bax inhibitor peptide V5	BIP-V5,BAX Inhibiting Peptide V5	BCL
	Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.		BCL
T8783	4-Methylbiphenyl	4-Phenyltoluene	Endogenous Metabolite
	4-Methylbiphenyl (4-Phenyltoluene) is a human endogenous metabolite.		Endogenous Metabolite
T21082	2,5-Dihydroxybiphenyl	TFIIH Modulator 12,TFIIH Modulator12	Others
	2,5-Dihydroxybiphenyl (TFIIH Modulator12), a small molecule destabilization inducer, induces the dimerization of trichothiodystrophy group A protein to modulate TFIIH transcriptional activity.		Others
T5111	4-Bromomethyl-2-cyanobiphenyl		Others
	4'-Bromomethyl-2-cyanobiphenyl is a halogenated benzonitrile used in protein-binding studies of quinoxaline angiotensin II receptor antagonists.		Others
T6231	Tebipenem Pivoxil	ME1211,Orapenem	Antibacterial , Antibiotic
	Tebipenem Pivoxil (Orapenem) , an orally activity carbapenem antibiotic, is utilized in treating otolaryngologic and respiratory infections.		Antibacterial , Antibiotic
T6307	Lubiprostone	SPI-0211,RU-0211	Chloride channel
	Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.		Chloride channel
T22638	CBiPES hydrochloride	CBiPES HCl	GluR
	CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ...		GluR
T17021	Tebipenem	LJC 11036	Antibiotic
	Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.		Antibiotic
TPL0366	4-Biphenylcarboxylic acid
	4-Biphenylcarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is TPL0366 and the CAS number is 92-92-2.
T60194	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide		Histone Methyltransferase
	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide is a potent and selective Enhancer of Zeste Homolog 2 (EZH2) inhibitor with I...		Histone Methyltransferase
T7913	2-Bromobiphenyl		Others
	2-Bromobiphenyl is a persistent organic pollutant (POP) found primarily in soil and water. It is a known human carcinogen and has been linked to a variety of health effects including reproductive and developmental toxici...		Others
T8332	Bipenquinate		Dehydrogenase
	Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.		Dehydrogenase
T5988	Dimethyl biphenyl-4,4'-dicarboxylate	Biphenyl dimethyl dicarboxylate	Others
	Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis.		Others
T40475	Ceftobiprole medocaril	BAL5788	Antibacterial
	Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA).		Antibacterial
T60041	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide		Microtubule Associated
	N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.		Microtubule Associated
T4654	(±)-Ibipinabant	(±)-BMS6462,SLV319,(±)-SLV319	Cannabinoid Receptor
	(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.		Cannabinoid Receptor