bch — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25140	BCH 2763	BCH2763,BCH-2763
	BCH 2763 is an effective, selective bifunctional thrombin inhibitor that blocks both the anion binding exosite and the active catalytic site.
T11820	LAT1-IN-1	BCH	Apoptosis , Others
	LAT1-IN-1 (BCH) (BCH) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. is a selective and competitive inhibitor of large neutral...		Apoptosis , Others
T0682	Lamivudine	GR109714X,BCH-189	HIV Protease , Reverse Transcriptase
	Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.		HIV Protease , Reverse Transcriptase
T8647	BCH001		DNA/RNA Synthesis
	BCH001 is a specific small-molecule inhibitor of PAPD5.		DNA/RNA Synthesis
T33891	PBI-1393	PBI1393,BCH1393,BCH 1393,BCH-1393,PBI 1393
	PBI-1393 can be used as an enhancer for Th1 type cytokine production and primary T cell activation.
T28833	SPD-756	SPD 756,BCH13520,BCH-13520,BCH 13520
	SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T29149	VX 759	VCH759,BCH27759,VX-759,VX759,VCH-759,BCH-27759
	VX 759, a nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection.
T17175	Troxacitabine	BCH-4556,SGX-145,SGX145,SPD-758,BCH4556,beta-L-OddC	Others
	Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious ...		Others
T61969	AChE/BChE-IN-10		AChR , AChE
	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation...		AChR , AChE
T60891	AChE/BChE/MAO-B-IN-1		MAO , AChE
	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1...		MAO , AChE
T62336	BChE-IN-3
	BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholin...
T60831	AChE/BChE-IN-3 hydrochloride
	AChE/BChE-IN-3 (BMC-1) hydrochloride is an AChE and BChE dual inhibitor. The IC50 values of AChE/BChE-IN-3 against equine serum BChE (eqBChE) and electric eel AChE (elAChE) is 0.383 μM and 6.08 μM, respectively [1].
T78799	BChE/HDAC6-IN-1		HDAC
	BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values of 4 nM for BChE and 8.9 nM for HDAC6. It demonstrates efficacy in alleviating cognitive deficits in an Aβ1–42...		HDAC
T61669	BChE-IN-4
	BChE-IN-4 is a highly potent inhibitor of the enzyme butyrylcholinesterase, capable of crossing the blood-brain barrier. It effectively reduces learning and memory impairments resulting from a deficiency in cholinergic a...
T75511	BChE-IN-10
	BChE-IN-10 (compound 6), isolated from Bletilla striata, is a potent mixed-type butyrylcholinesterase (BChE) inhibitor exhibiting an IC50 value of 6.4 μM. It is utilized in Alzheimer's disease (AD) research [1].
T78695	BChE-IN-16
	BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM. It demonstrates low cytotoxicity and potential for central nervo...
T62274	AChE/BChE-IN-2
	AChE/BChE-IN-2 (Compound 13b) is a potent inhibitor of AChE/BChE with IC50 values of 0.96 ± 0.14 μM and 1.23 ± 0.23 μM for AChE and BChE, respectively.
T73184	BChE-IN-15
	BChE-IN-15 is a compound characterized as a pseudo-irreversible, covalent inhibitor of butyrylcholinesterase (BChE), demonstrating potent activity with an inhibitory concentration (IC50) of 1.76 nM against human BChE (hB...
T62504	BChE-IN-8
	BChE-IN-8 (compound 20) is an orally active BChE (butyrylcholinesterase) inhibitor that crosses the blood-brain barrier and acts on eqBChE (IC50: 0.15 nM), hBChE (IC50: 45.2 nM). BChE-IN-8 can be used in the study of Alz...
T13242	UbcH5c-IN-1		Others
	UbcH5c-IN-1 is a selective small-molecule Ubiquitin-conjugating enzyme UbcH5c inhibitor (Kd: 283 nM for E2 UbcH5c-IN-1 by covalent binding with Cys85).		Others