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Search Results for " az3 "

9

Compounds

Cat No. Product Name Synonyms Targets
T10424 AZ-3 JAK
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
T4443 AZ32 ATM/ATR
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.
T5172 AZ304 c-Fms , Raf , p38 MAPK , Autophagy
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).
T19671 AZ31 AZ 31,AZ-31 ATM/ATR
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK f...
T2689 AZ3146 AZ 3146 Kinesin
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
TQ0012 AZ3451 Protease-activated Receptor
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
T23764 AZ3976 AZ 3976,AZ-3976 PAI-1
AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.
T71098 AZ3971
AZ3971 is a potent BACE1 inhibitor. AZ3971 blocks BACE1-mediated cleavage of APP and inhibits Aβ42 production HEK cells overexpressing the APP protein which carries the Swedish mutation (HEK.APPswe).
T62511 AZ3391
AZ3391 is a quinoxaline derivative that is a potent inhibitor of PARP. AZ3391 has potential for the study of diseases and conditions occurring in central nervous system tissues (e.g., brain and spinal cord).
TargetMol